Progress of Symptomatic Intracranial Hemorrhage after Intravenous Thrombolysis in Ischemic Stroke

doi:10.3969/j.issn.1673-5765.2018.12.016

Abstract

Abstract:

Bleeding transformation, especially symptomatic intracranial hemorrhage is an uncommon but serious complication after intravenous thrombolysis in the acute phase of ischemic stroke, which can lead to high disability and mortality. Thrombolysis rate of acute stroke in China was far lower than that in Europe and the United States, the main cause of which was for fear of hemorrhagic transformation risk. This article reviewed the symptomatic hemorrhage after thrombolysis, to provide a reference for safer thrombolytic therapy of acute stroke.

Key words: Ischemic stroke; Intravenous thrombolysis; Symptomatic intracranial hemorrhage;Predictive factor; Treatment

摘要：

出血转化，尤其症状性颅内出血是缺血性卒中患者急性期静脉溶栓后虽不常见但严重的并发症，其致残率和病死率均较高，严重影响患者预后。我国卒中急性期溶栓率远远落后于欧美国家，临床医生担心出血转化风险是主要原因。本文对溶栓后症状性颅内出血进行综述，以提高临床认识，更好地改进卒中急性期溶栓治疗。

关键词: 缺血性卒中; 静脉溶栓; 症状性颅内出血; 预测因素; 治疗

LIANG Zhi-Gang, YANG Shao-Wan, YU Guo-Ping. Progress of Symptomatic Intracranial Hemorrhage after Intravenous Thrombolysis in Ischemic Stroke[J]. Chinese Journal of Stroke, 2018, 13(12): 1301-1308.

梁志刚, 杨绍婉, 于国平. 缺血性卒中静脉溶栓后症状性颅内出血研究进展[J]. 中国卒中杂志, 2018, 13(12): 1301-1308.

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