Abstract: Objective To explore the effect of stenting of extra- and intra-cranial stenosis on cerebralwatershed infarction(CWI).Methods Total 61 patients(38 male, 23 female) with mean age 62±12 diagnosed as CWI by CT orMRI were taken endovascular stenting.Results Extra- and intra-cranial artery stenosis artery from common carotid artery(3 cases),internal carotid artery C1 segment (24 cases), C2 segment (3 cases), C5,C6 segment (10 cases), andcerebral middle artery (M1 segment, 21 cases); 37 lesions located at the left side and 24 at the rightside. All patients with total 65 offence arteries were taken endovascular stenting, and 98.4% of theoperations were successful. Bradycardia was observed during procedure in 3 cases, and recoveredafter medicine treatment. All the patients did not suffer from transient ischemia attach or strokeduring 6-12 months follow-up.Conclusion The stenting of extra- and intra-cranial artery may be an effective and safe therapy forcerebral watershed infarction. But large sample, prospective and randomized controlled trials willbe needed.

Key words: Cerebral watershed infarction; Angioplasty; Stenting; Bradycardia

摘要： 目的 探讨支架成形术治疗在颅内/外脑动脉狭窄所致脑分水岭梗死（CWI）中的应用效果。方法 对61例颅脑MRI或CT检查表现为CWI的患者伴有颅内/外动脉狭窄的患者行支架成形术治疗。男性38例，女性23例，平均年龄62±12岁。结果 CWI责任血管在颈总动脉3例；颈内动脉C1段24例，C2段3例，C5、C6段10例；大脑中动脉M1段21例；左侧病变37例，右侧病变24例。本组61例患者全部接受了支架成形术治疗，共涉及责任病变65处，手术成功率为98.4%。3例患者术中出现心动过缓，经对症治疗缓解。术后6～12个月随访无短暂性脑缺血发作（TIA）及新发脑梗死。结论 本研究结果提示支架成形术对颅内外动脉狭窄所致的CWI是安全的，可有效地预防缺血性事件的发生。但尚需进行大样本、前瞻性、随机对照研究证实。

关键词: 脑分水岭梗死; 血管成形术; 支架; 心动过缓