Table of Content

20 May 2007, Volume 2 Issue 05

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论著

Stenting of Atherosclerotic Intracranial Stenosis: A Six-month Follow-up Study

CHEN Kang-ning;SHI Shu-gui;FAN Wen-hui;et al.

2007, 2(05):  392-395. 

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Objective To analyze the preliminary short-term outcome, especially the effect on cognitivefunction, and the safety of stenting for intracranial artery stenosis.Methods Patients with intracranial artery stenting were monitored by transcranial Dopplersonography(TCD), mini-mental state examination(MMSE) and P300 before and 1, 3 and 6 monthsafter stenting.Results Total 52 patients with atherosclerotic intracranial artery stenosis were enrolled in our study.24 stenosis in M1 segment of middle cerebral artery and 28 in intracranial vertebral artery. Technicalsuccess was achieved in all patients, with no procedure-associated complications. The residualstenosis(7%±5%) after stenting reduced significantly compared with pre-procedure stenosis(78％±10%). At 1, 3 and 6 months after stenting, the scores of MMSE were significantly higher and thelatent phase of P300 were shortened significantly (P <0.01), especially at 6 months. The patients hadno recurrent transient ischemia attach or stroke, and TCD revealed no restenosis during 6 monthsfollow-up.Conclusion Stenting of intracranial artery stenosis may be safe, feasible and favorable fordecreasing ischemic events and improving cognitive function during short-term follow-up. But theeffect of long-term will be studied further.

Effect of Stenting of Extra- and Intra-cranial Artery Stenosis in Patient with Cerebral Watershed Infarction

SHUAI Jie;LIU Yong;LI Qian-ning;et al.

2007, 2(05):  396-399. 

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Objective To explore the effect of stenting of extra- and intra-cranial stenosis on cerebralwatershed infarction(CWI).Methods Total 61 patients(38 male, 23 female) with mean age 62±12 diagnosed as CWI by CT orMRI were taken endovascular stenting.Results Extra- and intra-cranial artery stenosis artery from common carotid artery(3 cases),internal carotid artery C1 segment (24 cases), C2 segment (3 cases), C5,C6 segment (10 cases), andcerebral middle artery (M1 segment, 21 cases); 37 lesions located at the left side and 24 at the rightside. All patients with total 65 offence arteries were taken endovascular stenting, and 98.4% of theoperations were successful. Bradycardia was observed during procedure in 3 cases, and recoveredafter medicine treatment. All the patients did not suffer from transient ischemia attach or strokeduring 6-12 months follow-up.Conclusion The stenting of extra- and intra-cranial artery may be an effective and safe therapy forcerebral watershed infarction. But large sample, prospective and randomized controlled trials willbe needed.

Stenting in Posterior Circulation Ischemia: A Clinical Analysis of 86 Cases

SHI Shu-gui;CHEN Kang-ning;FAN Wen-hui;et al.

2007, 2(05):  400-403. 

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Objective To evaluate the effects and safety of stenting for posterior circulation ischemia resultedfrom large artry occclusive diseases.Methods Patients of posterior circulation ischemia resulted from large artry occclusive diseaseswere treated with stenting since March, 2003 in our hospital, and we took a retrospective study onthe effects and follow-up results. Total 86 patients enrolled in our study, 58 males and 28 females,mean age 61±5 year.Results Among the 86 patients, two cases were resulted by dissecting aneurysm of V3 segment ofleft vertebral artery, one case was resulted from dissecting stenosis of the origin of left vertebralartery and 83 cases were resulted from atherosclerotic artery stenosis. The successful rate ofstenting was 97.7%. After 22.5±10.5 months follow-up, we found 4 cases of anterior circulationinfarct, 3 cases of posterior circulation infarct, 2 cases of posterior circulation transient ischemiaattach(TIA), 2 cases of cerebral hemorrhage and 3 cases of death. The incidence rate of ischemicaccidents in posterior circulation was 5.95%.Conclusion Stenting may be an effective therapy in the management of stenosis and dissectinganeurysm of the vertebrobasilar artery, and it can prevent posterior circulation ischemia.

Comparation of the Distribution of Intra- and Extra-cranial Artery Atherosclerosis Stenosis in Different Age Patients with Transient Ischemic Attack

LI Lin;ZHANG Lin-hong;XU Wuping;et al.

2007, 2(05):  404-406. 

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Objective To compare the distribution of intra-and extra-cranial artery atherosclerosis stenosis indifferent age patients with transient ischemic attack(TIA).Methods We calculated the frenquency of stenosis of the intra- and extra-cranial arteries in digitalsubtraction angiography of 64 patients with transient ischemic attack. The frenquency of stenosis ofarteries in various age groups was compared.Results Among 64 patients, cerebral artery atherosclerosis stenosis or occlusion was found in54 patients, and the frenquency of stenosis of intracranial artery was higher than extracranialartery (68.5% vs 64.8%). However, in patients less than 50 years old, the frenquency of stenosisof intracranial artery was significantly higher than extracranial artery and intra- and extra-cranialarteries (54.5% vs 27.3%, 18.2%, P <0.05), while in patients more than 50 years old, intracranialartery stenosis was significantly lower than intra- and extra-cranial stenosis and extracranialstenosis (21.9% vs 43.8%, 34.4%, P <0.05).Conclusion Cerebral artery atherosclerosis stenosis distributes characteristicly with age.

综述

Advance of Sleep Disorder after Stroke

LIU Guo-jun;CHEN Kang-ning

2007, 2(05):  459-462. 

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Sleep disorder is a severe and frequent complication in patients after stroke,whose features are high morbility and poor prognosis. Sleep disorder not only increases patients’sufferings, and interferes with patients' restoration, but also increases stroke recurrence risk. So more and more scholars pay attention to the post-stroke sleep disorder. Many researches are involved the observation of sleep disorder after stroke, as well as its mechanism disorder. This article will discuss these.