Abstract: Objective To compare the distribution of intra-and extra-cranial artery atherosclerosis stenosis indifferent age patients with transient ischemic attack(TIA).Methods We calculated the frenquency of stenosis of the intra- and extra-cranial arteries in digitalsubtraction angiography of 64 patients with transient ischemic attack. The frenquency of stenosis ofarteries in various age groups was compared.Results Among 64 patients, cerebral artery atherosclerosis stenosis or occlusion was found in54 patients, and the frenquency of stenosis of intracranial artery was higher than extracranialartery (68.5% vs 64.8%). However, in patients less than 50 years old, the frenquency of stenosisof intracranial artery was significantly higher than extracranial artery and intra- and extra-cranialarteries (54.5% vs 27.3%, 18.2%, P <0.05), while in patients more than 50 years old, intracranialartery stenosis was significantly lower than intra- and extra-cranial stenosis and extracranialstenosis (21.9% vs 43.8%, 34.4%, P <0.05).Conclusion Cerebral artery atherosclerosis stenosis distributes characteristicly with age.

Key words: Transient ischemic attack; Digital subtraction angiography; Atherosclerosis; Stenosis

摘要： 目的 探讨不同年龄组短暂性脑缺血发作（TIA）患者颅内、外动脉粥样硬化性狭窄的分布特征。方法 对64例TIA患者的全脑血管数字减影血管造影术（DSA）资料进行分析，计算颅内、外动脉狭窄的发生率，并对不同年龄患者颅内、外动脉狭窄或闭塞情况进行统计学比较。结果 64例患者中，54例（84%）存在脑动脉粥样硬化性狭窄，颅内动脉狭窄发生率略高于颅外动脉（68.5% vs 64.8%）。在<50岁组中，单纯颅内动脉狭窄或闭塞的发生率为54.5%，高于单纯颅外动脉（27.3%）及颅内-颅外动脉多发性狭窄或闭塞（18.2%）；而≥50岁组中，单纯颅内动脉狭窄或闭塞的发生率（21.9%）低于颅内-颅外狭窄或闭塞（43.8%）及单纯颅外动脉狭窄或闭塞(34.4%)，差异具有统计学差意义（P <0.05）。结论 TIA患者颅内、外动脉粥样硬化性狭窄随年龄变化而呈特征性分布。

关键词: 短暂性脑缺血发作; 数字减影血管造影术; 动脉粥样硬化; 狭窄