›› 2009, Vol. 4 ›› Issue (06): 454-4.

• 论著 • Previous Articles     Next Articles

Pilot Study of the Relationship between Cerebrovascular Stenosis and ABCD2 Score in Transient Ischemic Attack Patients

WANG Li-Feng, BI Qi, SONG Zhe   

  • Received:2009-02-17 Revised:1900-01-01 Online:2009-06-20 Published:2009-06-20
  • Contact: BI Qi

短暂性脑缺血发作患者ABCD2评分与脑血管狭窄相关性初步研究

王力锋,毕齐,宋哲   

  1. 100029 北京市首都医科大学附属北京安贞医院神经内科
  • 通讯作者: 毕齐

Abstract: Objective To evaluate the relationship between ABCD2 score and cerebrovacular stenosis of patients with transient ischemic attack(TIA).Methods We retrospectively reviewed the medical records of 88 patients with TIA; all of them were examined with the magnetic resonance angiography(MRA). All patients were divided into two groups according to cerebrovascular vascular stenosis ≥50% or not, and divided into two groups according to ABCD2 score ≥4 point or not. The relationship between ABCD2 score andcerebrovaculare vascular stenosis was analyzed.Results Group stenosis ≥50% were more likely to have ABCD2 score ≥4 compared with group stenosis <50%(74.4% vs 44.9%, OR =3.559, 95%CI 1.428-8.868, P =0.005). Group stenosis ≥50% were more likely to have stroke history than those stenosis <50%(33.3% vs 10.2%, OR =4.400,95%CI 1.408~4.869, P =0.01). The stroke within 2 days after TIA is higher in group cerebrovascular stenosis ≥50% than that in group stenosis <50%(10.3% vs 0%, OR =0.417, 95%CI 0.324-0.537,P =0.04).Conclusion The patients with ABCD2 score≥4 show higher rate of cerebrovascular stenosis. Patients with previous stroke more likely to undergo cerebrovascular vascular stenosis. The stroke within 2 days after TIA is higher in patients with cerebrovascualr stenosis ≥50%.

Key words: Ischemic attack; transient; ABCD2 score; Magnetic resonance angiography

摘要: 目的 评价短暂性脑缺血发作(transient ischemic attack,TIA)患者ABCD2评分和脑血管狭窄之间的关系。方法 回顾性研究了88例TIA患者ABCD2评分和颅脑磁共振血管成像(magnetic resonance angiography,MRA)影像资料,根据ABCD2评分分为评分≥4分组和评分<4分组,根据MRA评估分为血管狭窄≥50%组和狭窄<50%组,评价ABCD2评分与脑血管狭窄之间的相关性。结果 血管狭窄≥50%组与狭窄<50%组比较,ABCD2评分≥4分的比率增高[74.4% vs 44.9%,比值比(odds ratio,OR)3.559,95%可信区间(credibility interval,CI)1.428~8.868,P =0.005];既往有卒中病史的患者比率增高(33.3% vs 10.2%,OR =4.400,95%CI 1.408~4.869,P =0.01);脑血管狭窄≥50%组与狭窄<50%组比较,前者TIA后2d内卒中发生率明显增高(10.3% vs 0%,OR =0.417,95%CI 0.324~0.537,P =0.04)。结论 ABCD2评分≥4分MRA示颅内血管狭窄率高,既往有卒中病史的TIA患者颅内血管狭窄率增高,颅内血管狭窄≥50%TIA后2d内发生卒中的风险增高。

关键词: 脑缺血发作; 短暂性; ABCD2评分; 磁共振血管造影术