Abstract: Objective To investigate the efficacy of Urinary Kallikrein in patients with acute cerebralinfarction (ACI).Methods Sixty-two ACI patients were randomly divided into the control group and the UrinaryKallikrein group. Both groups of patients were received conventional therapy, such as anti-plateletaggregation and control of blood pressure. Besides the conventional therapy, The patients in theUrinary Kallikrein group also received Urinary Kallikrein treatment for 14 days. The patients wereevaluated by the neurologic function score, therapeutic efficiency and biochemical indicator beforeand after 14 days therapy.Results The neurologic functional recovery of the Urinary Kallikrein group obviously surpassedthan that of the control group. There was significantly different between the two groups after14 days therapy in the neurologic function score and the total efficiency (P =0.025 and P =0.021respectively). In the Urinary Kallikrein group, there was not significantly different between beforeand after 14 days therapy in biochemical indicator (P >0.05).Conclusion Urinary Kallikrein treatment on acute cerebral infarction was effective.

Key words: Brain Infarction; Urinary Kallikrein

摘要： 目的 探讨尤瑞克林治疗急性脑梗死的临床疗效。方法 将62例急性脑梗死患者随机分为对照组和尤瑞克林治疗组，两组均给予抗血小板聚集、控制血压等常规治疗，治疗组加用尤瑞克林治疗，共静脉滴注14d，观察两组患者治疗前及治疗后14d神经功能缺损程度、临床疗效及生化指标变化。结果 治疗组患者神经功能恢复明显优于对照组，两组治疗后神经功能评分比较，差异有统计学意义（P =0.025），两组临床疗效差异有统计学意义（P =0.021），治疗组治疗前后实验室指标无明显变化（P >0.05）。结论 尤瑞克林能有效治疗急性脑梗死。

关键词: 脑梗死; 尤瑞克林