Cognitive Impairment in Stroke Patients with Non-strategic Infarcts
2009, 4(03):
194-200.
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Objective To investigate the characters of cognitive impairment in patients with non-strategic infarcts(including subcortex, brain stem and cerebellar infarction) for once or twice in compared with healthy people.Methods We recruited 30 patients being at 3-6 months after stroke and 30 healthy volunteers matching by age, gender and education level. Cognition was assessed by neuropsychological tests,including mini-mental state examination(MMSE), California verbal learning test (CVLT), logical memory(LM), figure complex(FC), verbal fluency(VF), constructional praxis(CP), digit span(DS) and was compared between patients and controls as well as ability of daily living (ADL) and Hamilton rating scale for depression-17(HAMD-17).Results In comparison with controls, the stroke patients had significantly lower scores in MMSE(27.8±2.4 vs 28.9±0.9, P =0.021), also in the total score of the cognition(168.3±24.0 vs 188.8±25.4, P =0.002), CVLT(38.2±7.0 vs 43.1±8.0, P =0.016)and VF(43.8±10.6 vs 53.6±11.3, P =0.001).However, the patients’ performances in FC(41.2±7.1 vs 43.4±5.5, P =0.185), LM(21.6±5.6 vs 24.1±5.1,P =0.078), CP(Mann-Whitney Test, 11.0 vs 11.0, P =0.775) and DS(13.0±2.4 vs 13.9±2.8, P =0.171)were not significantly more impaired when compared with controls. The scores of ADL(26±9 vs 20±0,P =0.001) and HAMD-17(2.00 vs 0.00, P =0.000) were higher in the patients than in the controls.Conclusion Cognitive impairment of patients with non-strategic infarcts, compared with healthy volunteers, have been revealed, especially in the verbal memory and executive function, especially in executive function.
