Table of Content

20 December 2008, Volume 3 Issue 12

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主编手记

Personalized Medicine

WANG Yong-Jun

2008, 3(12):  871-4. 

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热点报道

Summary of the Sixth World Stroke Congress

Liu Li-Ping;Zhou Yong;Zhao Xing-Quan

2008, 3(12):  873-2. 

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述评

Enlightenment from the 2008 Latest Hypertension Studies in Stroke Prevention and Treatment

XU An-Ding;XIN Xiu-Feng

2008, 3(12):  875-5. 

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Implications of PRoFESS Results on Clinical Practice of Antiplatelet Therapy in Ischemic Stroke

WANG Yi-Long;WANG Chun-Xue;ZHAO Xing-Quan

2008, 3(12):  880-9. 

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论著

Effection of Special Clinic Follow-up on Hypertension Treatment and Optimal Hypertension Control rates in Stroke Patients

LIN Yan;LI Yan-Sheng;XU Qun;et al.

2008, 3(12):  889-6. 

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Objective To improve the management of hypertension in hypertensive stroke patients by stroke clinic follow-up.Methods 833 serial stroke patients with hypertension were enrolled in the study and were divided into two groups according to their follow-up status. The percentages of the patients that were treated by antihypertensive therapy as well as the percentages of the patients with optimal hypertension control were compared between two groups.Results Compared with the baseline, the rates of hypertension treatment and the optimal hypertension control were increased significantly during follow-up periods (from 40.5% to 92.1% and from 18.2% to 57.4%, respectively, P<0.01). Separately, the rates of hypertension treatment and the optimal hypertension control were significantly increased in the patients that were followed up in the stroke clinic from 41.0% to 98.4% as well as from 20.7% to 65.9% (P<0.01) .Meanwhile, those rates were also significantly increased in the patients that were telephone but not clinic followed up from 39.0% to 74.3% and from 11.5% to 33.5%(P<0.01). During the follow-up periods, the rate of combination therapy increased from 21.7% to 28.8% (P=0.013), as well as the rates of the patients with diet control(48.3% to 74.7%, P<0.01), keeping daily exercise(17.3% to 58.8%, P<0.001), keeping regular blood pressure measurement(24.7% to 46.7%, P<0.01), giving up smoking(76.5% to 94.4%, P<0.01), and drinking (77.1% to 88.8%, P=0.002)were increased significantly.Conclusion Stroke clinic follow-up can improve the hypertension management and life style changing among hypertensive stroke patients. The rates of antihypertensive treatment and the optimal hypertension control were better in those followed up in the special stroke clinic than those not in the clinic.

Cardiac Dysfunction Concomitant with Acute Cerebral Infarction and its Effect of Outcome: A Prospective Study of 150 Consecutive Cases

JIANG Bei-Si;CHEN Shu-Fen;WANG Liang;et al.

2008, 3(12):  895-6. 

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Objective To investigate the occurrence rates of cardiac complication after acute cerebral infarction, as well as the impact of cardiac complication on short-term and long-term effect.Methods We selected 150 consecutive inpatients suffering from cerebral infarction from 17 hospitials in shanghai. All these inpatients were examined within 48 hours of the onset of symptoms. The tests were performed on their admission to hospital, and thereafter on the seventh day. These tests incldue 12-lead ECG, serum level of enzymes including lactate dehydrogenase(LDH), creatine kinase(CK), creatine kinase isoenzyme-MB(CK-MB), aspartic acid transaminase(AST), troponin T(TnT), myoglobin(MHb). The patients will be followed up when they were discharged from hospitals using mRS, and 90±2 days later.Results Our study showed that 72.8% ECG were already abnormal while 81.8% in serum enzymes in patients with acute cerebral infarct. The abnormal ECG detected in patients with unfavourable short-term outcome reached to 82.0%, with a significant prevalence compared to 65.3% in favourable short-term outcome ones(P<0.05). Abnormality of serum level of enzymes showed no significant difference between patients with favourable or unfavourable short-term outcomes. While 90 days later, the serum level of enzymes indicated a higher ratio of abnormal conditions in patients with unfavourable outcome than those with favourlable outcome, especially the enzymes test taken on admission.Conclusion Our results indicate the high incidence of cardiac complication after acute cerebral infarction, and it will lead to an unfavourable prognosis of cerebral infarction, espetially when the abnormalisitions apperent during the first 48 hours.

Application of Intravascular Ultrasound in Carotid Atherosclerosis----Correlation with DSA and Histopathologic Findings

WAN Jie-Qing;LI Shan-Quan;JIANG Ji-Yao

2008, 3(12):  901-6. 

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Objective To compare intravascular ultrasound(IVUS) with digital subtractive angiography(DSA) and histopathologic findings of the carotid artery in vitro, and evaluate the role of IVUS in the diagnosis and treatment of carotid atherosclerotic disease.Methods 14 cervical carotid arteries were obtained in 7 cadavers. The vessel specimen was connected to the closed tubing system and continuously infused by 40% glycerin. DSA and IVUS were performed during infusion. Pathological examination was done, and statistical analysis were ensued.Results In the 14 cadaver carotid artery specimen, 42 pictures of IVUS were obtained and at the same 42 location, pathological examination were also done. In IVUS, 15 cases of atherosclerosis were detected, which was compatible with pathological examination. Ulcerative plaque was suspected in one case during IVUS examination, but no obvious abnormality was detected by pathological examination. The sensitivity and specificity of IVUS were 88% and 96% respectively. While in DSA examination, the sensitivity of mild atherosclerosis was only 47%. In the measurement of vascular diameter, there were no significantly statistical difference between DSA, IVUS and pathological examination.Conclusion IVUS can clearly show the characteristics of atherosclerosis of carotid artery, it can provide precise measurement of vascular diameter, severity and length of stenosis. As detecting early carotid atherosclerotic disease, IVUS is a very useful supplement while compared with DSA.

专题论坛

Effect of Hypertension on Cerebral Blood Flow and Antihypertensive Therapy in Cerebral Atherosclerosis

GAO Shan

2008, 3(12):  908-6. 

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High-Quality Antihypertension, Away From the Stroke

CHEN Lu-Yuan

2008, 3(12):  914-4. 

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Treatment of Hypertension in the Very Old People

ZENG Xue-Zhai;LIU De-Ping;Qi Hai-Mei

2008, 3(12):  920-4. 

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病例讨论

Anterior Spinal Artery Syndrome Caused by Aortic Dissection Stent Implantation

YAN Xin;SUN Yu-Heng;MA Zhi-Gang

2008, 3(12):  922-2. 

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指南与规范

Guidelines for Management of Ischaemic Stroke and Transient Ischaemic Attack 2008The European Stroke Organization (ESO) Executive Committee and the ESO Writing Committee ---- the Part of Primary Prevention

ZOU Xin-Ying;GAO Shan;HUANG Jia-Xing

2008, 3(12):  925-6. 

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综述

Potential Mechanisms for the Influences of Hyperglycemia on the Prognosis of Ischemic Stroke and Its Solutions

LI Zuo-Jun;ZHONG Li-Yong

2008, 3(12):  931-5. 

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Hyperglycemia increases morbidity and disability of acute ischemic stroke. There is no consensus on the target for the glycemic control in patients who had hyperglycemia after acute ischemic stroke. This article reviews the occurrence mechanisms of hyperglycemia in acute stroke and the potential mechanisms by which hyperglycemia influences outcomes. We also summarize and discuss the solutions and suggestions on management of hyperglycemia after acute ischemic stroke, which are proposed by relevant associations in China and abroad recently.

Scientific Use of Multimedia Technology to Improve Vascular Neurology Teaching Quality

ZHAO Xing-Quan;WANG Yong-Jun;WANG Chun-Xue

2008, 3(12):  936-3. 

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How to Correctly Interpret the Medical Literature and the Results of Clinical Trials ----- the experience about evaluating the results of carotid artery stenting (CAS) clinical trial

JIANG Wei-Jian

2008, 3(12):  939-5. 

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