关键词: 体层摄影术; X线计算机; CO2激发实验; 后循环; 脑血流储备

Abstract: Objective To explore the feasibility of the cerebrovascular reserve assessment with gantry angled perfusion computed tomography(CT) and carbon dioxide(CO2) test in patients with posterior circulation hemodynamic impairment.Methods Perfusion CT with 5% CO2 and 95% oxygen(O2) was used to investigate 9 symptomic vertebral-basilar artery stenosis patients with posterior circulation hemodynamic impairment. CT gantry angle was selected from -13 degree to -23.5 degree (mean -14.7±1.7degree) for the purpose that base line paralleled to vertical line of the level. This protocol could avoid bone artifacts furthest.Results The cerebrovascular reserve of brainstem ranged from -19.83% to 53.36% and of cerebellum ranged from -20.58% to 45.50%.Conclusion It is safe and feasible to assess cerebrovascular reserve with gantry angled perfusion CT and CO2 test in patients with posterior circulation hemodynamic impairment.

Key words: Tomography; X-ray computed; CO2 Test; Posterior circulation; Cerebrovascular reserve