›› 2011, Vol. 6 ›› Issue (03): 243-247.

• 综述 • 上一篇    下一篇

幽门螺杆菌与动脉粥样硬化

杨旭1,郑志东1,李新毅2,许贤豪3   

  1. 1北京市航天中心医院(北京大学航天临床医学院)神经内科2山西医科大学第一医院神经内科3北京医院神经内科
  • 收稿日期:2010-04-14 修回日期:2010-03-14 出版日期:2011-03-20 发布日期:2011-03-20
  • 通讯作者: 李新毅

Helicobacter Pylori and Atherosclerosis

YANG Xu, ZHENG Zhi-Dong, LI Xin-Yi, et al

  

  • Received:2010-04-14 Revised:2010-03-14 Online:2011-03-20 Published:2011-03-20
  • Contact: LI Xin-Yi

摘要: 幽门螺杆菌(Helicobacter pylori,Hp)与慢性胃炎、消化性溃疡胃黏膜相关淋巴样组织淋巴瘤以及胃腺癌等胃肠疾病密切相关,近年来研究发现Hp亦可导致心脑血管疾病的发生,相应机制可能是通过促血管动脉粥样硬化形成,具体表现在促全身炎性反应、促代谢紊乱等方面,本文即从生物学特征以及致病机制两方面对Hp与动脉粥样硬化的关系作一综述。

关键词: 螺杆菌; 幽门; 动脉粥样硬化; 诊断; 治疗

Abstract: Helicobacter pylori (Hp) can cause gastritis, peptic ulcer and gastric cancer. Therehas been increasing evidence that the prevalence of Hp infection may be increased in patientswith stroke that is due to atherosclerosis. Several pathogenic mechanisms could help to explainthis association. Inflammatory response and metabolic disorder induced by Hp may promoteatherosclerotic process. This article reviews biological characteristics and pathogenic mechanism ofassociation between Hp infection and atherosclerosis.

Key words: Helicobacter pylori; Atherosclerosis; Diagnosis; Therapy