卒中杂志 ›› 2012, Vol. 7 ›› Issue (12): 948-952.
王柳清,邵蓓,王虹
收稿日期:
2012-02-07
出版日期:
2012-12-20
发布日期:
2012-12-20
基金资助:
出血性脑卒中大鼠hNSCs脑内移植后新生血管生成与运动功能恢复之机制研究——国家自然基金(2011,81171088)
Received:
2012-02-07
Online:
2012-12-20
Published:
2012-12-20
王柳清,邵蓓,王虹. 血管新生与缺血性卒中的相关性研究进展[J]. 卒中杂志, 2012, 7(12): 948-952.
WANG Liu-Qing, SHAO Bei, WANG Hong. Recent Advance on Relationship Between Angiogenesis and Ischemic Stroke[J]. Chinese Journal of Stroke, 2012, 7(12): 948-952.
1Folkman J, Merler E, Abernathy C, et al. Isolation of a tumor factor responsible for angiogenesis[J]. J Exp Med, 1971, 133:275-288.2 Patan S. Vasculogenesis and angiogenesis as mechanisms of vascular network formation, growth and remodeling[J]. J Neurooncol, 2000, 50:1-15.3 Risau W. Mechanisms of angiogenesis[J]. Nature, 1997, 386:671-674.4 Greenberg DA. Angiogenesis and stroke[J]. Drug News Perspect, 1998, 11:265-270.5 Kilarski WW, Gerwins P. A new mechanism of blood vessel growth-hope for new treatment strategies[J]. Discov Med, 2009, 8:23-27.6 Makanya AN, Hlushchuk R, Djonov VG. Intussusceptive angiogenesis and its role in vascular morphogenesis, patterning, and remodeling[J]. Angiogenesis, 2009, 12:113-123.7 Caduff JH, Fischer LC, Burri PH. Scanning electron microscope study of the developing microvasculature in the postnatal rat lung[J]. Anat Rec, 1986, 216:154-164.8 Crivellato E, Nico B, Vacca A, et al. Recombinant human erythropoietin induces intussusceptive microvascular growth in vivo[J]. Leukemia, 2004, 18:331-336.9 Potente M, Gerhardt H, Carmeliet P. Basic and therapeutic aspects of angiogenesis[J]. Cell, 2011, 146:873-887.10 Krupinski J, Kaluza J, Kumar P, et al. Role of angiogenesis in patients with cerebral ischemic stroke[J]. Stroke, 1994, 25:1794-1798.11 Chen J, Zhang ZG, Li Y, et al. Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats[J]. Circ Res, 2003, 92:692-699.12 Wang Z, Tsai LK, Munasinghe J, et al. Chronic valproate treatment enhances postischemic angiogenesis and promotes functional recovery in a rat model of ischemic stroke[J]. Stroke, 2012, 43:2430-2436.13 Zhang ZG, Chopp M. Neurorestorative therapies for stroke:underlying mechanisms and translation to the clinic[J]. Lancet Neurol, 2009, 8:491-500.14 Zhang Z, Chopp M. Vascular endothelial growth factor and angiopoietins in focal cerebral ischemia[J]. Trends Cardiovasc Med, 2002, 12:62-66.15 Zhang ZG, Zhang L, Tsang W, et al. Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemia[J]. J Cereb Blood Flow Metab, 2002, 22:379-392.16 Chen HH, Chien CH, Liu HM. Correlation between angiogenesis and basic fibroblast growth factor expression in experimental brain infarct[J]. Stroke, 1994, 25:1651-1657.17 Manoonkitiwongsa PS, Jackson-Friedman C, Mcmillan PJ, et al. Angiogenesis after stroke is correlated with increased numbers of macrophages:the clean-up hypothesis[J]. J Cereb Blood Flow Metab, 2001, 21:1223-1231.18 Wei L, Erinjeri JP, Rovainen CM, et al. Collateral growth and angiogenesis around cortical stroke[J]. Stroke, 2001, 32:2179-2184.19 Zhang ZG, Zhang L, Jiang Q, et al. VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain[J]. J Clin Invest, 2000, 106:829-838.20 Guo H, Itoh Y, Toriumi H, et al. Capillary remodeling and collateral growth without angiogenesis after unilateral common carotid artery occlusion in mice[J]. Microcirculation, 2011, 18:221-227.21 Liman TG, Endres M. New vessels after stroke:postischemic neovascularization and regeneration[J]. Cerebrovasc Dis, 2012, 33:492-499.22 Oladipupo S, Hu S, Kovalski J, et al. VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting[J]. Proc Natl Acad Sci USA, 2011, 108:13264-13269.23 Kovacs Z, Ikezaki K, Samoto K, et al. VEGF and flt. Expression time kinetics in rat brain infarct[J]. Stroke, 1996, 27:1865-1872; discussion 1863-1872.24 Jin KL, Mao XO, Greenberg DA. Vascular endothelial growth factor:direct neuroprotective effect in in vitro ischemia[J]. Proc Natl Acad Sci USA, 2000, 97:10242-10247.25 Sun Y, Jin K, Xie L, et al. VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia[J]. J Clin Invest, 2003, 111:1843-1851.26 Marti H J, Bernaudin M, Bellail A, et al. Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia[J]. Am J Pathol, 2000, 156:965-976.27 Hayashi T, Abe K, Itoyama Y. Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia[J]. J Cereb Blood Flow Metab, 1998, 18:887-895.28 Yang JP, Liu HJ, Liu XF. VEGF promotes angiogenesis and functional recovery in stroke rats[J]. J Invest Surg, 2010, 23:149-155.29 Dietrich WD, Danton G, Hopkinsa C, et al. Thromboembolic events predispose the brain to widespread cerebral infarction after delayed transient global ischemia in rats[J]. Stroke, 1999, 30:855-861; discussion 862.30 Ginsberg MD, BustoR. Rodent models of cerebral ischemia[J]. Stroke, 1989, 20:1627-1642.31 Taguchi Y, Takashima S, Sasahara E, et al. Morphological changes in capillaries in the ischemic brain in Wistar rats[J]. Arch Histol Cytol, 2004, 67:253-261.32 Jin KL, Mao XO, Nagayama T, et al. Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain[J]. Neuroscience, 2000, 99:577-585.33 Lee MY, Ju WK, Cha J H, et al. Expression of vascular endothelial growth factor mRNA following transient forebrain ischemia in rats[J]. Neurosci Lett, 1999, 265:107-110. 34 Leon RL, Li X, Huber JD, et al. Worsened outcome from middle cerebral artery occlusion in aged rats receiving 17beta-estradiol[J]. Endocrinology, 2012, 153:3386-3393.35 Brenneman M, Sharma S, Harting M, et al. Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats[J]. J Cereb Blood Flow Metab, 2010, 30:140-149.36 Jin K, Mao X, Xie L, et al. Delayed transplantation of human neural precursor cells improves outcome from focal cerebral ischemia in aged rats[J]. Aging Cell, 2010, 9:1076-1083.37 Jin K, Minami M, Xie L, et al. Ischemia-induced neurogenesis is preserved but reduced in the aged rodent brain[J]. Aging Cell, 2004, 9:373-377.38 Shen F, Fan Y, Su H, et al. Adeno-associated viral vector-mediated hypoxia-regulated VEGF gene transfer promotes angiogenesis following focal cerebral ischemia in mice[J]. Gene Ther, 2008, 15:30-39.39 Zhu W, Fan Y, Frenzel T, et al. Insulin growth factor-1 gene transfer enhances neurovascular remodeling and improves long-term stroke outcome in mice[J]. Stroke, 2008, 39:1254-1261.40 Kusaka N, Sugiu K, Tokunaga K, et al. Enhanced brain angiogenesis in chronic cerebral hypoperfusion after administration of plasmid human vascular endothelial growth factor in combination with indirect vasoreconstructive surgery[J]. J Neurosurg, 2005, 103:882-890.41 Bellomo M, Adamo EB, Deodato B, et al. Enhancement of expression of vascular endothelial growth factor after adeno-associated virus gene transfer is associated with improvement of brain ischemia injury in the gerbil[J]. Pharmacol Res, 2003, 48:309-317.42 Ozawa CR, Banfi A, Glazer NL, et al. Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis[J]. J Clin Invest, 2004, 113:516-527.43 van Bruggen N, Thibodeaux H, Palmer JT, et al. VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain[J]. J Clin Invest, 1999, 104:1613-1620.44 Wang Y, Kilic E, Kilic U, et al. VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena[J]. Brain, 2005, 128:52-63.45 Ferrara N, Alitalo K. Clinical applications of angiogenic growth factors and their inhibitors[J]. Nat Med, 1999, 5:1359-1364.46 Simons M. Angiogenesis:where do we stand now?[J]. Circulation, 2005, 111:1556-1566. |
[1] | 曹黎明, 任力杰. 急性缺血性卒中诊疗技术的进展与展望[J]. 中国卒中杂志, 2024, 19(9): 983-989. |
[2] | 符鹏程, 曹黎明, 朱佳倩, 赵桂玉, 徐格林. 大动脉粥样硬化性缺血性卒中再灌注治疗的研究进展[J]. 中国卒中杂志, 2024, 19(9): 1004-1011. |
[3] | 张丽苹, 曹黎明, 肖楠, 廖雨琦, 池枫, 余艳妮, 任力杰. 纳米材料在缺血性卒中诊疗中的研究进展及挑战[J]. 中国卒中杂志, 2024, 19(9): 1012-1017. |
[4] | 王晓蕊, 骆嵩, 邹良玉, 屈洪党, 崔雪, 赵玉洁. 嗜酸性粒细胞与单核细胞比值预测急性缺血性卒中患者静脉溶栓预后的价值研究 [J]. 中国卒中杂志, 2024, 19(9): 1025-1033. |
[5] | 王铄, 余苹, 张宁, 王春雪. 2013—2023年缺血性卒中与睡眠相关性研究的文献计量学分析 [J]. 中国卒中杂志, 2024, 19(9): 1040-1047. |
[6] | 周宏宇, 李子孝, 王拥军. 基于影像组学预测大脑年龄与缺血性卒中的研究进展[J]. 中国卒中杂志, 2024, 19(9): 1066-1076. |
[7] | 阿娜古丽·阿不拉尼压孜, 吴晓欣, 李骄星, 李竹浩, 盛文利. 急性缺血性卒中磁敏感血管征影响因素及临床应用的研究进展[J]. 中国卒中杂志, 2024, 19(9): 1077-1085. |
[8] | 杨金波, 张聪. 高分辨率血管壁成像在缺血性卒中患者中的应用进展[J]. 中国卒中杂志, 2024, 19(9): 1086-1093. |
[9] | 吴春艳, 尹雅诗, 王广志, 岳奎涛. 急性缺血性卒中不同时间窗影像学评价及应用进展[J]. 中国卒中杂志, 2024, 19(9): 1094-1101. |
[10] | 张梦若, 徐守臣, 隋翠翠, 李玉奎, 王雪莉. 下肢康复机器人联合头针治疗对老年缺血性卒中患者步行效率和协调功能影响调查 [J]. 中国卒中杂志, 2024, 19(8): 902-908. |
[11] | 吴娱倩, 张玉梅, 臧大维, 范小伟, 王安心, 张晓丽, 孟霞. 上肢动作研究测试量表评定亚急性期缺血性卒中患者偏瘫侧上肢及手功能的信效度和敏感性研究 [J]. 中国卒中杂志, 2024, 19(8): 915-923. |
[12] | 莫秋红, 丁晓波, 李靓, 张岩波, 李伟荣. 基于可解释性机器学习模型的轻型缺血性卒中复发预测研究[J]. 中国卒中杂志, 2024, 19(8): 924-930. |
[13] | 逯丹, 陈玮琪, 王雅平, 段婉莹, 郭蕾, 王玲, 刘丽萍, 徐安定, 王拥军, 中国卒中学会脑保护圆桌会学术委员会. 缺血性卒中脑细胞保护科学声明——来自中国卒中学会的科学声明 [J]. 中国卒中杂志, 2024, 19(8): 938-955. |
[14] | 李光硕, 赵性泉. 《中国急性缺血性卒中诊治指南2023》解读[J]. 中国卒中杂志, 2024, 19(8): 956-961. |
[15] | 白磊鹏, 罗杰, 周思捷, 黄健辉, 梁铭钦, 赵庆顺. 肺叶楔形切除术后并发急性缺血性卒中行介入取栓治疗2例并文献回顾 [J]. 中国卒中杂志, 2024, 19(8): 962-966. |
阅读次数 | ||||||
全文 |
|
|||||
摘要 |
|
|||||