关键词: 对比增强经颅多普勒超声; 右向左分流; 正常人群

Abstract:

【Abstract】 Objective To observe the incidence, shunt volume, shunt type of normal population, and compare RLS feature between two age groups. Methods Collect the clinical data of normal people who volunteered to undergo contrast-enhanced transcranial Doppler (cTCD). They are classified into two groups: young group (18 to 45 years old) and middle age group (more than 45 years old). Take the physiological saline activating via elbow intravenous injection as a contrast agent, and combine with Valsalva maneuver, diagnose RLS with mpTCD monitoring and grade the shunt volume. The distribution characteristics of different shunt volume and shunt type (the inherent and potential) in the study population were also analyzed. Results A total of 195 normal people were enrolled in our study, and RLS rate was 28.7%, with 39 cases as minor shunt (20%). RLS rate in young group was 28.9% (39/135), and RLS rate in middle age group 28.3% (17/60). There were no statistical differences between two groups in RLS rate and shunt volume distribution, and minor shunts take a predominate percent in all those shunts. Thirty four cases were inherent type (60.7%), and 22 cases potential type (39.3%). In young group, 25 cases were inherent type (64.0%), and 14 cases potential type (35.9%); in middle age group, 9 cases were inherent type (52.9%), and 8 cases potential type (47.1%). There was no statistical difference between two groups in shunt type distribution. Conclusion The incidence of RLS in the selected population in our study is about 28.7%, and the minor shunt takes a predominate percent. There are no significant differences between young group and middle age group in RLS incidence, shunt volume and shunt type.

Key words: Contrast-enhanced transcranial Doppler; Right-to-left shunt; Normal population