Research Progress of Diagnostic Biomarkers Related to Cerebral Infarction

doi:10.3969/j.issn.1673-5765.2017.12.021

Abstract

Abstract:

In current clinical practice, diagnosis of stroke mainly depends on the physical examination of symptoms and signs as well as imaging examinations. However, many diseases such as migraine, epilepsy may have similar symptoms with stroke, and imaging examination also has certain degree of limitations. With the development of science and technology, more and more diagnostic biomarkers related to cerebral infarction are found, especially the study on nascent proteomics and miRNA family has guiding significance in the diagnosis of cerebral infarction.

Key words: Cerebral infarction; Biomarker; Early diagnosis; Proteomics; miRNA

摘要：

在目前临床实践中，卒中的诊断主要依靠临床医师对症状、体征的判断及影像学检查，但是许多疾病如偏头痛、痫性发作等可能与卒中有类似的临床表现，影像学客观检查也有一定的局限性。随着科学技术的不断进步，越来越多与脑梗死相关的诊断性生物标记物被发现，特别是新生蛋白质组及miRNA家族生物标记物的研究，对临床脑梗死的诊断有指导意义。

关键词: 脑梗死; 生物标记物; 早期诊断; 蛋白质组; miRNA

GAO Shuo-Jun,ZHANG Xiang-Jian, ZHANG Pei-Pei. Research Progress of Diagnostic Biomarkers Related to Cerebral Infarction[J]. Chinese Journal of Stroke, 2017, 12(12): 1154-1157.

高硕君，张祥建，张培培. 脑梗死相关诊断性生物标记物研究进展[J]. 中国卒中杂志, 2017, 12(12): 1154-1157.

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