Advance in IL-33/ST2 Signal Pathway in Stroke

doi:10.3969/j.issn.1673-5765.2019.04.018

Abstract

Abstract:

The IL-33/ST2 signal pathway is closely related to stroke. This signal pathway not only involves in the atherogenesis, but also in stroke occurrence and development, inflammation reaction after stroke and prognosis of stroke. This article reviewed the advance in role of IL-33/ST2 signal pathway in stroke, to provide ideas for future research and clinical practice.

Key words: Interleukin-33; Inflammation; Biomarker; Stroke

摘要：

IL-33/ST2信号通路与卒中关系密切。该信号通路不仅可以影响动脉粥样硬化，还可以影响卒中的发病、严重程度、卒中后炎症反应及预后转归。本文就IL-33/ST2信号通路在卒中中的研究进展进行阐述，旨在为今后研究和临床实践提供思路。

关键词: 白细胞介素-33; 炎症; 生物标志物; 卒中

TIAN Xuan, PEI Lu-Lu, WANG Xiao, LIU Xin-Jing, XU Yu-Ming,SONG Bo. Advance in IL-33/ST2 Signal Pathway in Stroke[J]. Chinese Journal of Stroke, 2019, 14(04): 385-388.

田璇，裴璐璐，王潇，刘新静，许予明，宋波. IL-33/ST2信号通路与卒中[J]. 中国卒中杂志, 2019, 14(04): 385-388.

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