Research Progress in Endovascular Treatment for Symptomatic Non-Acute Internal Carotid Artery Occlusion

doi:10.3969/j.issn.1673-5765.2025.02.015

Abstract

Abstract: The basic treatment for patients with symptomatic non-acute internal carotid artery occlusion includes antiplatelet drugs, intensive lipid-lowering, and risk factors control. However, even with the best medical treatment, these patients still have a high rate of stroke recurrence. In recent years, with the maturity of technology and the update of devices, endovascular treatment has been gradually used in the treatment of symptomatic non-acute internal carotid artery occlusion, but high-level evidence-based medical evidence is still lacking. This review aims to describe the research progress in endovascular treatment for symptomatic non-acute internal carotid artery occlusion, including its efficacy and safety, patient selection, and its effect on cognitive function.

Key words: Non-acute internal carotid artery occlusion; Chronic internal carotid artery occlusion; Endovascular treatment; Ischemic stroke; Cognitive function

摘要： 症状性非急性颈内动脉闭塞患者的基础治疗是抗血小板药物、强化降脂及危险因素的控制，但即使接受最佳的内科治疗，此类患者仍有较高的卒中复发率。近年来，随着技术的成熟以及器械的更新，血管内治疗逐渐用于症状性非急性颈内动脉闭塞的治疗，但仍缺乏高级别循证医学证据的支持。本文旨在阐述症状性非急性颈内动脉闭塞在血管内治疗方面的研究进展，包括其有效性和安全性、患者选择及其对认知功能的影响。

关键词: 非急性颈内动脉闭塞; 慢性颈内动脉闭塞; 血管内治疗; 缺血性卒中; 认知功能

CLC Number:

YANG Yingying, GAO Ying, MO Dapeng, WANG Yilong. Research Progress in Endovascular Treatment for Symptomatic Non-Acute Internal Carotid Artery Occlusion[J]. Chinese Journal of Stroke, 2025, 20(2): 240-246.

杨营营, 高颖, 莫大鹏, 王伊龙. 症状性非急性颈内动脉闭塞血管内治疗研究进展[J]. 中国卒中杂志, 2025, 20(2): 240-246.

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