Analysis of the Trend in the Burden of Ischemic Stroke Attributable to High BMI in China and Globally from 1990 to 2021

doi:10.3969/j.issn.1673-5765.2025.01.012

Abstract

Abstract: Objective To analyze the current status and trend of the burden of ischemic stroke attributable to high BMI in China and globally from 1990 to 2021.
Methods Based on the 2021 global burden of disease database, data on disability-adjusted life years (DALYs) and deaths related to ischemic stroke attributable to high BMI were extracted. This paper described the total number of DALYs and deaths due to strokes caused by high BMI in China in 2021, and the age-standardized mortality rate, as well as the trend changes from 1990 to 2021. The Joinpoint regression model was used to calculate the average annual percent change in standardized DALY rate and mortality in China and globally from 1990 to 2021.
Results From 1990 to 2021, the number of deaths due to ischemic stroke attributable to high BMI in China increased from 7171 to 44 263, and the DALYs increased from 211 600 person-years to 1 188 200 person-years, which increased by 5.17 times and 4.61 times, respectively. Globally, the corresponding increases were 0.95 times and 1.08 times. The annual percent change for China’s age-standardized mortality rate and age-standardized disability-adjusted life years was 2.67% and 2.69%, respectively, showing a significant upward trend.
Conclusions Since 1990, the burden of ischemic stroke attributable to high BMI in China has significantly increased, indicating the growing public health pressure caused by high BMI. In contrast, global indicators have remained relatively stable.

Key words: High body mass index; Ischemic stroke; China; Disease burden; Disability-adjusted life year

摘要： 目的分析1990—2021年中国和全球由高BMI导致的缺血性卒中疾病负担的现状与趋势。
方法基于2021年全球疾病负担研究数据库提取高BMI相关缺血性卒中伤残调整生命年（disability-adjusted life year，DALY）和死亡数据，描述2021年中国高BMI导致的卒中DALY和死亡总数及年龄标化死亡率，以及1990—2021年的变化趋势，并采用Joinpoint回归模型计算中国和全球1990—2021年标化DALY率和死亡率的平均年度变化百分比。
结果 1990—2021年，中国由高BMI导致的缺血性卒中死亡人数从7171人增至44 263人，DALY从21.16万人年增至118.82万人年，分别增加了5.17倍和4.61倍；而全球相应增长为0.95倍和1.08倍。中国的年龄标化死亡率和年龄标化的伤残调整生命年年度变化百分比分别为2.67%和2.69%，呈显著上升趋势。
结论 1990年以来，中国由高BMI导致的缺血性卒中疾病负担显著上升，这显示出高BMI给我国公共卫生体系带来的压力日益增大；相较之下，全球整体相关指标则相对平稳。

关键词: 高体重指数; 缺血性卒中; 中国; 疾病负担; 伤残调整生命年

CLC Number:

LIU Qiankun, LI Pengyao, MA Li, DAI Jingjiao, XU Yang, PANG Jiaxue, HUANG Juju, XIE Hui. Analysis of the Trend in the Burden of Ischemic Stroke Attributable to High BMI in China and Globally from 1990 to 2021[J]. Chinese Journal of Stroke, 2025, 20(1): 95-103.

刘乾坤, 李鹏鹞, 马丽, 戴婧佼, 徐洋, 庞佳雪, 黄菊菊, 谢晖. 1990—2021年中国和全球归因于高BMI的缺血性卒中疾病负担变化趋势分析[J]. 中国卒中杂志, 2025, 20(1): 95-103.

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