A Case of Isolated Symptomatic Basilar Artery Stenosis with Imaging Reversal

doi:10.3969/j.issn.1673-5765.2025.06.013

Chinese Journal of Stroke ›› 2025, Vol. 20 ›› Issue (6): 769-774.DOI: 10.3969/j.issn.1673-5765.2025.06.013

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A Case of Isolated Symptomatic Basilar Artery Stenosis with Imaging Reversal

LU Qingli, SUN Chao, SONG Chensheng, LIU Guozheng, LIU Pei, LIU Yan, CHANG Qiaoqiao, LIN Xuemei, WU Songdi

Department of Neurology and Neuro-Ophthalmology, The First Hospital of Xi’an (The First Affiliated Hospital of Northwest University), Xi’an Key Laboratory for Innovation and Translation of Neuroimmunological Diseases, Xi’an 710002, China

Received:2024-05-07 Online:2025-06-20 Published:2025-06-20
Contact: WU Songdi, E-mail: wusongdi@gmail.com

影像学逆转的孤立症状性基底动脉狭窄1例

逯青丽，孙超，宋沉生，刘国正，刘佩，刘燕，常乔乔，蔺雪梅，吴松笛

西安 710002 西安市第一医院（西北大学附属第一医院）神经内科和神经眼科，西安市神经免疫疾病创新转化重点实验室

通讯作者: 吴松笛 wusongdi@gmail.com
基金资助:
陕西省科技计划项目（2022SF-507；2023-YBSF-048；2023-YBSF-052）
陕西省中医药管理局项目（2022-SLRH-LJ-013）
西安市科技计划项目（22YXYJ0074）

Abstract

Abstract: There is limited research on isolated symptomatic basilar artery stenosis (ISBAS), and the treatment strategies remain unclear. This article reported the process of diagnosis and treatment of an ISBAS patient whose imaging findings ultimately reversed after six months of aggressive medical therapy. The patient presented with mild neurological deficits at the onset of the disease, but the condition rapidly deteriorated after admission. Vascular examination revealed subtotal occlusion of the basilar artery. The patient refused endovascular treatment and was given dual antiplatelet therapy and high-intensity statin therapy for six months. Follow-up MRA examinations at 3 and 6 months showed progressive improvement in basilar artery stenosis, ultimately leading to its reversal.

Key words: Isolated symptomatic basilar artery stenosis; Antiplatelet; Lipid-lowering treatment; Imaging reversal

摘要： 孤立症状性基底动脉狭窄（isolated symptomatic basilar artery stenosis，ISBAS）的相关研究较少，治疗方案尚不明确。本文报道1例ISBAS患者经积极药物治疗6个月后，影像学最终发生逆转的诊疗经过。该患者发病时为轻度神经功能缺损，入院后病情迅速恶化，影像学检查显示基底动脉次全闭塞。患者拒绝血管内治疗，予以双联抗血小板药物治疗及高强度他汀类药物治疗6个月。治疗3个月和6个月随访的MRA检查显示，患者基底动脉狭窄逐渐改善，最终逆转。

关键词: 孤立症状性基底动脉狭窄; 抗血小板治疗; 降脂; 影像学逆转

CLC Number:

LU Qingli, SUN Chao, SONG Chensheng, LIU Guozheng, LIU Pei, LIU Yan, CHANG Qiaoqiao, LIN Xuemei, WU Songdi. A Case of Isolated Symptomatic Basilar Artery Stenosis with Imaging Reversal[J]. Chinese Journal of Stroke, 2025, 20(6): 769-774.

逯青丽, 孙超, 宋沉生, 刘国正, 刘佩, 刘燕, 常乔乔, 蔺雪梅, 吴松笛. 影像学逆转的孤立症状性基底动脉狭窄1例[J]. 中国卒中杂志, 2025, 20(6): 769-774.

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A Case of Isolated Symptomatic Basilar Artery Stenosis with Imaging Reversal

影像学逆转的孤立症状性基底动脉狭窄1例

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