Chinese Journal of Stroke ›› 2013, Vol. 8 ›› Issue (01): 40-44.

Previous Articles     Next Articles

Helicobacter Pylori-induced Inflammation and Immune Responses Promote the Development of Atherosclerosis  

  

  1. *Department of Neurology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
  • Received:2012-09-25 Online:2013-01-20 Published:2013-01-20

幽门螺杆菌感染与动脉粥样硬化相关炎症及免疫反应

胡震1,丁素菊1,曲乐丰2   

  1. 1200433 上海
    上海第二军医大学附属长海医院神经内科
    2上海第二军医大学附属长征医院血管外科
  • 通讯作者: 曲乐丰 qulefeng@163.com
  • 基金资助:

    上海市科委“创新行动计划”基础研究重点项目基金(12JC1411202)
    上海市科委青年科技启明星跟踪项目
    (11QH1403000)

Abstract:

Helicobacter pylori infection is widely spread in the population. In recent years, the correlation between Helicobacter pylori infection and atherosclerotic disease has received increasing attention. The inflammatory response is the basis of atherosclerosis. The inflammation and immune responses caused by Helicobacter pylori infection can affect some cytokines, which may contribute to the occurrence and development of atherosclerosis. This paper reviews inflammatory factors associated with Helicobacter pylori infection and atherosclerosis to provide a reference for prevention and treatment of atherosclerotic artery diseases.

Key words: Atherosclerosis; Helicobacter pylori; Inflammation; Stroke; C-reactive protein

摘要:

幽门螺杆菌感染在人群中广泛存在,近年来幽门螺杆菌感染与动脉粥样硬化性疾病的相关性研究受到了越来越多的关注。炎症反应是动脉粥样硬化的基础,幽门螺杆菌感染引起的炎症和免疫反应可使体内多种与动脉粥样硬化相关的因子产生变化,从而可能促进动脉粥样硬化的发生和进展。本文就幽门螺杆菌感染与动脉粥样硬化相关的因子做一综述,为动脉粥样硬化性疾病的防治提供参考。

关键词: 动脉粥样硬化; 螺杆菌; 幽门; 炎症; 卒中; C反应蛋白