Relationship between Homocysteine Metabolism and Ischemic Stroke

Abstract

Abstract:

Hyperhomocysteinemia was believed to be an independent risk factor for ischemic stroke. Based on the background of homocysteine metabolic pathways, with homocysteine and related lipid causing arterial sclerosis as foundmental basis, this article elaborates the relationship between homocysteine and ischemic stroke. As discussed, there is a positive correlation between the level of homocysteine and the severity of ischemic stroke. There are different conclusions whether the lower homocysteine caused by vitamins can or cannot affect the prognosis of stroke. The results of the studies remain controversial on the relationship between hyperhomocysteinemia and various subtypes of ischemic stroke.

Key words: Homocysteine; Hyperhomocysteinemia; Ischemic stroke

摘要：

高同型半胱氨酸血症被认为是卒中的独立危险因素。本文以同型半胱氨酸代谢途径为背景，以同型半胱氨酸及相关血脂致动脉粥样硬化为基础，阐述同型半胱氨酸与缺血性卒中的关系。其中，同型半胱氨酸水平与卒中的严重程度成正比，维生素降低同型半胱氨酸对卒中预后的影响各研究结果不一。高同型半胱氨酸血症与各型缺血性卒中的关系研究结果仍存在争议。

关键词: 同型半胱氨酸; 高同型半胱氨酸血症; 缺血性卒中

LI Qian, ZHOU Yun-Tao, TIAN Wei, et al.. Relationship between Homocysteine Metabolism and Ischemic Stroke[J]. Chinese Journal of Stroke, 2014, 9(09): 797-802.

李茜，周云涛，田卫，等. 型半胱氨酸的代谢与缺血性卒中的相互关系[J]. 中国卒中杂志, 2014, 9(09): 797-802.

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