Progress of Studies Relevant to the Roles of Micro Ribonucleic Acids in Ischemic Stroke

Abstract

Abstract:

Recent years, it has been found that micro ribonucleic acids(miRNAs) is a type of RNA proteins which has special role in the regulation of gene expression. Recent studies also found that a few of miRNAs performed unique roles in the etiology, diagnosis, and treatment of ischemic stroke. We summarized researches on the roles of miRNAs related to multiple risk factors, biological marker, and treatment of ischemic stroke, in order to provide reference and helpfor future basic and clinical studies on stroke relevant to miRNAs.

Key words: Micro ribonucleic acids; Ischemic stroke; Biological marker; Neuroprotection

摘要：

微小核糖核酸（micro ribonucleic acids，miRNAs）是近年来发现的一类对基因表达调控具有调节作用的核糖核酸（ribonucleic acid，RNA）分子，近年来研究发现部分miRNAs在缺血性卒中的病因、诊断、治疗等方面具有独特的作用。本文对有关缺血性卒中的多种危险因素、生物学标记物以及治疗手段等方面的miRNAs相关研究做一综述，以期能够为miRNAs相关的卒中基础、临床研究提供参考。

关键词: 微小核糖核酸; 缺血性卒中; 生物学标记物; 神经保护

LI Hai-Long, BI Xiao-Ying. Progress of Studies Relevant to the Roles of Micro Ribonucleic Acids in Ischemic Stroke[J]. Chinese Journal of Stroke, 2015, 10(11): 974-979.

李海龙，毕晓莹. 微小核糖核酸在缺血性卒中研究中的进展[J]. 中国卒中杂志, 2015, 10(11): 974-979.

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