Stroke in Behçet's Disease

doi:10.3969/j.issn.1673-5765.2017.05.011

Abstract

Abstract:

Behçet's syndrome (BD) is a immune-mediated small-vessel systemic vasculitis. Neuro-Behçet's disease (NBD), involving central nervous system damage in 2.5%-49% of BD cases, is an important factor resulting in poor outcome of BD. It is usually classified as parenchymal and non-parenchymal NBD, the latter also known as vascular NBD. In vascular NBD, besides common cerebral venous sinus thrombosis, other forms of vascular damage such as ischemic or hemorrhagic stroke, intracranial artery dissection, aneurysm and ischemic optic neuropathy have been reported, and the lesions have involved in brain parenchyma, beyond the range of vascular NBD in traditional definition. Advances in clinical characteristics and diagnosis of stroke related to different types of BD are reviewed in this article.

Key words: Stroke; Behçet's Disease

摘要：

白塞病（Behçet's disease，BD）是一种累及全身多系统的慢性炎症性疾病。神经白塞病（neuro-Behçet's disease，NBD）在BD发病率中占2.5%～49%，是导致BD预后差的重要因素。NBD通常分为脑实质型和非脑实质型（后者也称血管性NBD），在血管性NBD中，除了常见的颅内静脉窦血栓形成之外，也陆续有报道其他缺血性或出血性卒中以及颅内动脉夹层、动脉瘤、缺血性视神经病等不同类型的血管损害，病变位置已经涉及脑实质，扩展了以前血管性NBD定义的范畴。BD相关卒中临床表现各异，易被忽视或误诊，本文对BD相关卒中的临床特点及诊断的研究进展进行回顾。

关键词: 卒中; 白塞病

YANG Qing-Lin, WANG Jia-Wei, LAI Chun-Tao. Stroke in Behçet's Disease[J]. Chinese Journal of Stroke, 2017, 12(05): 432-435.

杨庆林，王佳伟，赖春涛. 白塞病相关卒中[J]. 中国卒中杂志, 2017, 12(05): 432-435.

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