Abstract:

Objective To analyze the possible risk factors of non-atherosclerotic lacunar infarction (NALI). Methods 106 NALI patients were included. The ratio of sex and the percentage of smoking, hypertension, type 2 diabetes, hypercholesterolemia, high level of low density lipoprotein cholesterol in serum of all patients were analyzed. Results The male-to-female ratio of all patients was 1.58:1, and this rate was 1.07:1 in 85 nonsmoking patients. All of 21 smokers were male (32.31% in all male patients). The percentage of hypertension, diabetes, hypercholesterolemia, high level of low density lipoprotein cholesterol in serum were 70.75% (N=75), 48.11% (N=51), 36.79% (N=39) and 39.62% (N=42), respectively. Conclusion Hypertension, Diabetes, hypercholesterolemia, high level of low density lipoprotein cholesterol in serum may play a key role in the development of NALI, and they may be risk factors of NALI.while smoking may play an important role in male NALI patients.

Key words: Lacunar infarction; Hypertension; Diabetes; Smoking; Blood lipid

摘要：

目的 分析非动脉粥样硬化性腔隙性脑梗死（non-atherosclerotic lacunar infarction，NALI）患者可能 的高危因素。 

方法 回顾性调查106例NALI 患者。分析了其性别比例以及吸烟、高血压病、2型糖尿病、高胆固醇 血症、高低密度脂蛋白血症患者在所有NALI患者中所占的比例。 

结果 所有NALI患者中，男女比例为1.58∶1，85例非吸烟患者中男女比例为1.07∶1。本研究中的吸 烟患者全部为男性，共21例，占所有男性患者的32.31%。高血压病、2型糖尿病、高胆固醇血症、高低 密度脂蛋白血症患者比例分别为70.75%（75例）、48.11%（51例）、36.79%（39例）和39.62%（42例）。 

结论 高血压病、2型糖尿病、高胆固醇血症、高低密度脂蛋白血症可能在NALI 发生中起到重要作 用，吸烟可能与男性NALI 有关。

关键词: 腔隙性脑梗死; 高血压; 糖尿病; 吸烟; 血脂