【Abstract】
Objective To explore the feasibility of three dimensional flow-dephasing-prepared fast spoiled gradient recalled echo(3D FDP-FSPGR) in detecting the laque of intracranial artery using 3.0T MR scanner.
Methods Ten patients with intracranial artery stenosis >70% confirmed by digital subtraction angiography were enrolled in this study. 3D FDP-FSPGR and two dimensional double inversion recovery(2D DIR) were performed in all patients. The contrast-noise-ratio, the lumen area and plaque area which the two sequences were measured and compared.
Results The contrast-noise-ratio of 3D FDP-FSPGR was 10.16±4.28 and 2D DIR was 14.81±5.26, there were no statistically significant differences etween the two sequences(t =2.03, P <0.05). Lumen area and plaque area from 3D FDP-FSPGR and 2D DIR techniques highly correlated(ICCs of 0.96 and 0.95, respectively). The results measured of two sequences were 2.2±1.2 mm2 and 2.2±1.3 mm2 for lumen area, 18.8±1.4 mm2 and 18.5±0.9 mm2 for plaque area, respectively. The scan ranges of two sequences were 48 mm and 8 mm, respectively, and the scan time were 3.7 minutes and 4.8 minutes, spectively.
Conclusions 3D FDP-FSPGR is able to acquire the three dimensional wall images of main intracranial arterial trunk with larger coverage in shorter scan time compared with 2D DIR. It may provide more comprehensive accurate information for clinical therapeutic because of the satisfying image quality and reliable technology.
