中国卒中杂志 ›› 2017, Vol. 12 ›› Issue (04): 364-369.DOI: 10.3969/j.issn.1673-5765.2017.04.016

• 综述 • 上一篇    下一篇

卒中动物模型的研究进展

尹春雨,朱东亚   

  1. 211166 南京南京医科大学药学院药理学教研室
  • 收稿日期:2016-12-07 出版日期:2017-04-20 发布日期:2017-04-20
  • 通讯作者: 朱东亚 dyzhu@njmu.edu.cn
  • 基金资助:

    国家自然科学基金优秀青年项目(81222016)

Research Progress in Animal Models of Stroke

  • Received:2016-12-07 Online:2017-04-20 Published:2017-04-20

摘要:

卒中是当今世界上发病率、致残率和致死率最高的重大疾病之一,其病理机制以及预防治疗措施仍然是目前研究的热点。卒中动物模型对于卒中的病理机制及其防治的研究具有重要意义。本文针对传统的和改良的卒中动物模型的制备方法及其优缺点进行综述。

文章导读: 本文结合国内外最新的研究进展,总结了传统的和改良的缺血性和出血性卒中动物模型的制备方法及其优缺点,并对未来卒中动物模型的研究做出展望。

关键词: 卒中; 动物模型; 方法

Abstract:

Stroke is one of the major diseases in the world due to its the highest morbidity, disability rate and mortality. The pathological mechanism and prevention treatment are still research focus. Animal model of stroke is of great significance in the pathogenesis and its prevention of the research. This paper aims to summarize the preparation method of traditional and modified models of stroke and its advantages and disadvantages.

Key words: Stroke; Animal models; Method