[1] WANG W，JIANG B，SUN H，et al. Prevalence，

incidence，and mortality of stroke in China：results

from a nationwide population-based survey of 480 687

adults[J]. Circulation，2017，135（8）：759-771.

[2] RIEGEL B，MOSER D K，BUCK H G，et al.

Self-care for the prevention and management of

cardiovascular disease and stroke：a scientific

statement for healthcare professionals from

the American Heart Association[J/OL]. J Am

Heart Assoc，2017，6（9）：e006997. https：//doi.

org/10.1161/JAHA.117.006997.

[3] MESCHIA J F，BUSHNELL C，BODEN-ALBALA

B，et al. Guidelines for the primary prevention of stroke：a statement for healthcare professionals from

the American Heart Association/American Stroke

Association[J]. Stroke，2014，45（12）：3754-3832.

[4] 中华医学会神经病学分会脑血管病学组. 中国脑血

管病一级预防指南2015[J]. 中华神经科杂志，2015，

48（8）：629-643.

[5] WHELTON P K，CAREY R M，ARONOW W

S，et al. 2017 ACC/AHA/AAPA/ABC/ACPM/

AGS/APhA/ASH/ASPC/NMA/PCNA Guideline

for the Prevention，Detection，Evaluation，and

Management of High Blood Pressure in Adults：A

Report of the American College of Cardiology/

American Heart Association Task Force on

Clinical Practice Guidelines[J/OL]. Hypertension，

2018，71（6）：e13-e115. https：//doi.org/10.1161/

HYP.0000000000000065.

[6] O'DONNELL M J，CHIN S L，RANGARAJAN

S，et al. Global and regional effects of potentially

modifiable risk factors associated with acute stroke

in 32 countries（INTERSTROKE）：a case-control

study[J]. Lancet，2016，388（10046）：761-775.

[7] GUPTA A，GIAMBRONE A E，GIALDINI G，et

al. Silent brain infarction and risk of future stroke：a

systematic review and meta-analysis[J]. Stroke，2016，

47（3）：719-725.

[8] SMITH E E，SAPOSNIK G，BIESSELS G J，et

al. Prevention of stroke in patients with silent

cerebrovascular disease：a scientific statement

for healthcare professionals from the American

Heart Association/American Stroke Association[J/

OL]. Stroke，2017，48（2）：e44-e71. https：//doi.

org/10.1161/STR.0000000000000116.

[9] 中华医学会神经病学分会脑血管病学组. 中国缺血

性脑卒中风险评估量表使用专家共识[J]. 中华神经

科杂志，2016，49（7）：519-525.

[10] LI L，GERAGHTY O C，MEHTA Z，et al. Agespecific

risks，severity，time course，and outcome

of bleeding on long-term antiplatelet treatment after

vascular events：a population-based cohort study[J].

Lancet，2017，390（10093）：490-499.

[11] BIBBINS-DOMINGO K，U. S. Preventive Services

Task Force. Aspirin use for the primary prevention

of cardiovascular disease and colorectal cancer：U.

S. preventive services task force recommendation

statement[J]. Ann Intern Med，2016，164（12）：836-

845.

[12] 宋田. 缺血性卒中的一级预防指南[J]. 中国卒中杂志，

2006，1（3）：210-212.

[13] PIGNONE M，ALBERTS M J，COLWELL J A，et

al. Aspirin for primary prevention of cardiovascular

events in people with diabetes：a position statement of the American Diabetes Association，a scientific

statement of the American Heart Association，and

an expert consensus document of the American

College of Cardiology Foundation[J]. Circulation，

2010，121（24）：2694-2701.

[14] MOSCA L，BANKA C L，BENJAMIN E J，et al.

Evidence-based guidelines for cardiovascular disease

prevention in women：2007 update[J]. Circulation，

2007，115（11）：1481-1501.

[15] STONE N J，ROBINSON J G，LICHTENSTEIN A

H，et al. 2013 ACC/AHA guideline on the treatment

of blood cholesterol to reduce atherosclerotic

cardiovascular risk in adults：a report of the

American College of Cardiology/American Heart

Association Task Force on Practice Guidelines[J].

Circulation，2014，129（25 Suppl 2）：S1-45.

[16] MACH F，RAY K K，WIKLUND O，et al. Adverse

effects of statin therapy：perception vs. the evidence

- focus on glucose homeostasis，cognitive，renal and

hepatic function，haemorrhagic stroke and cataract[J/

OL]. Eur Heart J，2018. https：//doi.org/10.1093/

eurheartj/ehy182.

[17] 他汀类药物防治缺血性卒中/短暂性脑缺血发作专

家共识组. 他汀类药物防治缺血性卒中/短暂性脑

缺血发作专家共识[J]. 中国卒中杂志，2013，8（7）：

565-575.

[18] JANUARY C T，WANN L S，ALPERT J S，et al.

2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation：a report of the

American College of Cardiology/American Heart

Association Task Force on practice guidelines

and the Heart Rhythm Society[J/OL]. Circulation，

2014，130（23）：e199-e267. https：//doi.org/10.1161/

CIR.0000000000000041.

[19] MARQUARDT L，GERAGHTY O C，MEHTA

Z，et al. Low risk of ipsilateral stroke in patients

with asymptomatic carotid stenosis on best medical

treatment：a prospective，population-based study[J/

OL]. Stroke，2010，4l（1）：e11-e17. https：//doi.

org/10.1161/STROKEAHA.109.561837.

[20] SMETANA G W，SCHERMERHORN M，

MUKAMAL K J. Should we screen this patient for

carotid artery stenosis?：grand rounds discussion

from Beth Israel Deaconess Medical Center[J]. Ann

Intern Med，2017，167（7）：484-492.

[21] KERNAN W N，OVBIAGELE B，BLACK H R，et

al. Guidelines for the prevention of stroke in patients

with stroke and transient ischemic attack：a guideline

for healthcare professionals from the American Heart

Association/American Stroke Association[J]. Stroke，

2014，45（7）：2160-2236.

[22] RIMMELE D L，LARENA-AVELLANEDA A，

ALEGIANI A C，et al. Real-world experience of

treatment decision-making in carotid stenosis in a

neurovascular board[J]. Neurology，2017，89（4）：

399-407.