阻塞性睡眠呼吸暂停低通气综合征与醒后卒中之间关系的研究进展

doi:10.3969/j.issn.1673-5765.2019.04.010

摘要/Abstract

摘要：

醒后卒中（wake-up stroke，WUS）患者通常由于发病时间不确切而延误包括静脉溶栓在内的超早期治疗，并且WUS与清醒时发病的缺血性卒中相比在危险因素及发病机制等方面尚存在差异。因此，了解WUS的危险因素并且早期干预具有重要意义。目前，关于WUS危险因素的研究表明OSAHS是 WUS的重要危险因素之一，但是OSAHS引起WUS的机制尚未阐明。本文就目前OSAHS与WUS之间关系的研究进展进行综述。

文章导读： 本文对OSAHS与WUS的关系及可能的病理生理机制作了重点阐述，并指出目前研究中存在的主要问题，为未来学者在探讨OSAHS与WUS关系方面的研究提供参考。

关键词: 醒后卒中; 阻塞性睡眠呼吸暂停低通气综合征; 缺血性卒中

Abstract:

Due to the uncertain onset time, wake-up stroke (WUS) patients are usually excluded from thrombolytic therapy. There were still some differences in risk factors and pathogenesis between WUS and stroke occurring while awake. It's important to investigate the related risk factors and give timely intervention for WUS. Now many studies confirmed that OSAHS was one of the important risk factors of WUS, while the mechanism of OSAHS causing WUS is still unclear. This article reviewed the advance in the relationship between OSAHS and WUS.

Key words: Wake-up stroke; Obstructive sleep apnea hypopnea syndrome; Ischemic stroke

傅翔，李洁，刘昱璐，吴嘉靖，刘春风. 阻塞性睡眠呼吸暂停低通气综合征与醒后卒中之间关系的研究进展[J]. 中国卒中杂志, 2019, 14(04): 352-356.

FU Xiang,LI Jie, LIU Yu-Lu, WU Jia-Jing, LIU Chun-Feng. Advance in Correlation of Obstructive Sleep Apnea Hypopnea Syndrome and Wake-up Stroke[J]. Chinese Journal of Stroke, 2019, 14(04): 352-356.

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