关键词: 小的深部脑梗死; 交界区梗死; 腔隙性梗死; 大动脉病变

Abstract: Small deep cerebral infarcts, often referred to lacunes，have been traditionally associated withsmall-vessel disease affecting the deep penetrating arterial system. However, small deep cerebralinfarcts with ipsilateral large cerebral artery disease are often observed. The aim of this articleis to investigate the relationship between the small deep cerebral infarcts and the large arterydisease. This article reviewed 21 pieces of related literatures aboard which discussed the pattern ofcerebral infarcts in stenotic or occluded cerebral arteries of anterior circulation, and the potentialmechanisms of small deep cerebral infarcts caused by large artery disease. Large cerebral arterydisease can also cause the small deep cerebral infarcts like “lacunar infarcts”.

Key words: Small deep cerebral infarcts; Border-zone infarcts; Penetrating artery infarcts; Large cerebral artery disease