关键词: 经颅多普勒; 大脑中动脉; 支架成形术; 微栓子

Abstract: Objective TCD was applied to detect the microemboli signal during the middle cerebral arteryangioplasty and stenting procedure.Methods Eight consecutive patients (3 females and 5 males, average age 45.5±10.5 years old)were selected in the study since Jan 2006 to Dec 2006. The data was recorded and emphasizedduring the four phases as follows: (1) putting guide catheter; (2) sending microwire through thelesion; (3) stenting delivering system span across the lesion; and (4) primary balloon dilatationperiod. TCD was used continually in this stenting implantation period to record the microemboliof middle cerebral arteries simultaneously, also to record the peak systolic velocity before and afterthe stenting.Results There were no complications related to the procedure. The percentage of stenosis was79.4%±7.8% preoperation, and 9.4%±8.2% postoperation. Peak systolic velocity where the stenosislocated was 305.3±61.5cm/s preoperation, 201.1±40.5cm/s immediately postoperation. Highintensitytransient signals indicative of microemboil could be observed in all four phases (3.5±4.2,8.9±7.2, 4.6±5.8 and 14.5±7.0, respectively), but appeared to be more frequent in the phase 4.Conclusion Angioplasty and stenting implantation is a method in the treatment of the middlecerebral artery stenosis, and can improve cerebral blood flow. Although high-intensity transient signalsare observed in these cases, the relationship between high-intensity transient signals and ischemicevents need to be further explored.

Key words: Transcranial Doppler; Middle cerebral artery; Angioplasty; Microemboli