›› 2008, Vol. 3 ›› Issue (09): 658-661.

• 论著 • 上一篇    下一篇

支架置入术对椎基底动脉系统短暂性脑缺血发作患者诱发电位的影响

陈启东   

  1. 100050 北京市首都医科大学附属北京天坛医院神经内科
  • 收稿日期:2008-07-09 修回日期:1900-01-01 出版日期:2008-09-20 发布日期:2008-09-20
  • 通讯作者: 陈启东

Effect of Stent on Evoked Potentials in Patients with Vertebrobasilar Transient Ischemia Attack

  • Received:2008-07-09 Revised:1900-01-01 Online:2008-09-20 Published:2008-09-20

摘要: 目的 观察支架置入术能否改善椎基底动脉系统短暂性脑缺血发作(TIA)患者的亚临床症状。方法 11例症状性椎基底动脉狭窄的椎基底动脉系统TIA患者,支架置入术前后分别检测体感诱发电位(SEP)、脑干听觉诱发电位(BAEP)、视觉诱发电位(VEP),记录各诱发电位的潜伏期及波幅。结果 (1)术前诱发电位均异常,主要表现为SEP N20及P40潜伏期异常,BAEPⅠ、Ⅲ、Ⅴ波潜伏期延长,VEP P100潜伏期延长。(2)与术前相比,术后1周BAEP表现为Ⅰ~Ⅲ波潜伏期缩短(P =0.046)、Ⅲ波幅升高(P =0.05);SEP表现为N20潜伏期缩短(P =0.012),N13~N20间期缩短(P =0.013),P14~N20间期缩短(P =0.005);VEP表现为 P100潜伏期缩短(P =0.022)。结论 支架置入术后,椎基底动脉系统TIA患者的SEP、BAEP、VEP好转,提示患者的亚临床症状恢复。

关键词: 椎基底动脉; 支架置入术; 诱发电位

Abstract: Objective To evaluate whether stent could improve the recovery of subclinical symptom of patients with vertebrobasilar transient ischemia attack.Methods A series of 11 patients who underwent stenting for vertebrobasilar transient ischemia attack patients with symptomatic vertebrobasilar artery stenosis was investigated in this study. All patients were evaluated with somatosensory evoked potential, brainstem auditory evoked potential, as well as visual evoked potential both before and after stent placement. Latency and wave amplitude of evoked potentials before and after stent placement were analysed for significance.Results We found abnormal evoked potential before the stenting, especially prolonged latency of N20 and P40 in somatosensory evoked potential (SEP), of wave I, III and V in brainstem auditory evoked potential (BAEP), and of P100 in visual evoked potential (VEP). While after the procedure evoked potential showed that in BAEP the latency of I-III wave significantly decreased (P =0.046) and the amplitude of wave III increased significantly (P =0.05); In SEP the latency of N20 was shortened (P =0.012) and the intervals of N13-N20 (P =0.013) and P14-N20 (P =0.005) were both decreased; In VEP the latency of P100 was shortened significantly (P =0.022).Conclusion somatosensory evoked potential, brainstem auditory evoked potential, and visual evoked potential of patients with vertebrobasilar transient ischemia attack were improved after stenting. Stenting is may be helpful to the recovery of subclinical symptom.

Key words: Stent placement; Vertebrobasilar artery; Evoked potential