›› 2009, Vol. 4 ›› Issue (06): 519-5.

• 综述 • 上一篇    下一篇

脑血管痉挛活体动物模型的研究进展

贾莉,张磊,孙保亮

  

  1. 1272013 山东省济宁市济宁医学院临床学院2金乡县人民医院神经内科3泰山医学院附属医院神经内科
  • 收稿日期:2009-03-17 修回日期:1900-01-01 出版日期:2009-06-20 发布日期:2009-06-20
  • 通讯作者: 贾莉

Progress in Animal Models of Cerebral Vasospasm in vivo

JIA Li*, ZHANG Lei, SUN Bao-Liang.   

  1. *Department of Clinical College, Jining Medical College, Jining, Shandong 272013,China
  • Received:2009-03-17 Revised:1900-01-01 Online:2009-06-20 Published:2009-06-20
  • Contact: JIA Li

摘要: 蛛网膜下腔出血引起的脑血管痉挛是导致蛛网膜下腔出血患者不良预后的主要原因之一,其发生机制至今尚未完全明了。因此,寻找一种理想的蛛网膜下腔出血后脑血管痉挛动物模型将对脑血管痉挛发生机制及临床防治的研究起到巨大的推动作用,但目前尚无一种用于研究蛛网膜下腔出血后症状性脑血管痉挛的理想模型。本文就应用各种动物制作脑血管痉挛模型的研究进展进行综述。

关键词: 蛛网膜下腔出血; 血管痉挛; 颅内; 模型; 动物

Abstract: 【Abstract】 Cerebral vasospasm caused by subarachnoid hemorrhage is a major cause of poor prognosis, but the pathogenesy has not been understood completely until now. Therefore, establishing an ideal animal model of cerebral vasospasm following subarachnoid hemorrhage will have an enormous advanced effect on research of pathogenesy, clinical prevention and cure of cerebral vasospasm. However, there is still not an ideal model used for studying symptomatic cerebral vasospasm following subarachnoid hemorrhage. The author reviewed the advancement of different animal models of cerebral vasospasm.

Key words: 【Key Words】 Subarachnoid hemorrhage; Vasospasm; intracvanial; Model; animal