›› 2011, Vol. 6 ›› Issue (07): 519-523.

• 论著 • 上一篇    下一篇

急性缺血性视网膜病与急性大脑半球缺血事件危险因素对比研究

王虔1,贾楠1,卢宁2,田国红1,王莹2,冀鸿涛3,张晓君1   

  1. 1北京市首都医科大学附属北京同仁医院神经内科2首都医科大学附属北京同仁医院眼科中心3首都医科大学附属北京同仁医院影像中心
  • 收稿日期:2011-03-04 修回日期:2011-02-04 出版日期:2011-07-20 发布日期:2011-07-20
  • 通讯作者: 张晓君

Comparison of Risk Factors in Patients with Retinal and Hemisphere Ischemic Event

WANG QIAN, JIA Nan, LU Ning, et al   

  • Received:2011-03-04 Revised:2011-02-04 Online:2011-07-20 Published:2011-07-20
  • Contact: ZHANG Xiao-Jun

摘要: 目的 比较急性视网膜缺血事件(acute retinal ischemic event,ARIE)与急性大脑半球缺血事件(acutehemisphere ischemic event,AHIE)危险因素异同,为针对性预防干预提供依据。方法 单中心临床病例横断面描述性研究。收集2008年1月至2009年1月确诊的ARIE连续病例(ARIE组)和同期AHIE住院的连续病例(AHIE组)。采集所有入组患者临床基本信息及危险因素情况,比较两组的危险因素。结果 共收集ARIE病例124例,AHIE病例126例。ARIE组与AHIE组比较发现,ARIE组平均年龄53±16岁,较AHIE组平均年龄67±12岁低(P<0.01);性别、吸烟史、饮酒史、高脂血症、缺血性心脏病史在ARIE与AHIE组差异无统计学意义。高血压(P<0.01)、糖尿病(P =0.016)、心脏瓣膜病(P =0.048)、卒中史(P =0.001)、心房颤动(P =0.007)在ARIE组比AHIE组少见,而重度颈动脉狭窄(≥70%)或闭塞在ARIE组较AHIE组常见[ARIE对于AHIE:优势比(odds ratio,OR),2.3;95%可信区间(confidence interval,CI)1.110~4.682,P =0.025]。结论 ARIE发病年龄相对较低,高血压、糖尿病、心脏瓣膜病、卒中史、心房颤动在AHIE多见,而重度颈动脉狭窄多见于ARIE。

关键词: 视网膜; 脑缺血; 危险因素; 颈动脉疾病

Abstract: Objective To compare the differences of risk factor between acute retinal ischemic event(ARIE)and acute hemisphere ischemic event(AHIE).Methods Single center, cross-section descriptive study. Consecutive cases of acute ischemicretinopathy patients(ARIE) and acute ischemic cerebrovascular disease patients(AHIE) werecollected prospectively from January 2008 to January 2009. Clinical data were recorded and databetween ARIE and AHIE were compared and statistically analyzed by SPSS11.5 software.Results Totally 124 ARIE cases and 126 AHIE patients were included. ARIE patients(53±16yearsold) were statistically younger than AHIE patients(67±12 years old)(P <0.01). No statisticallysignificant difference regard to gender, smoking, alcohol, hyperlipidemia, ischemic heart diseasewas found between ARIE and AHIE(P >0.05). Hypertension(P <0.01), diabetes mellitus(P =0.016),valvular heart diseases(P =0.048), stroke(P =0.001) and atrial fibrillation(P =0.007) were statisticallymore common in AHIE patients than in ARIE patients, while severe carotid artery stenosis/occlusion was statistically more common in ARIE than in AHIE[ARIE versus AHIE:odds ratio(OR),2.3; 95% confidence interval(CI), 1.110 to 4.682, P =0.025].Conclusion History of Hypertension, diabetes mellitus, valvular heart diseases, cerebral strokeand atrial fibrillation were more common in AHIE while carotid artery stenosis/occlusion wasstatistically more common in ARIE.

Key words: Retinal; Brain ischemia; Risk factors; carotid artery diseases