关键词: 脑缺血发作; 短暂性; ABCD2评分; 预测; 危险因素

Abstract: Objective To assess the predictive accuracy of the ABCD2 score for the severity of early recurrentevents after transient ischemic attack (TIA).Methods We completed a prospective, hospital-based study of 488 consecutive patients presentingwith TIA. Recurrent TIA, minor stroke, and major stroke (National Institutes of Health Stroke Scalescore>3) were identified within 7 days after TIA. Predictive value was expressed as the area underthe receiver operating characteristic curve (AUC).Results Of 488 patients with TIA were involved in study, 49 had a recurrent TIA (10.04%; 95%CI ,6.78% to16.12%), 23 had a recurrent minor stroke (4.71%; 95%CI , 1.96% to 6.37%) and 25 hada recurrent major stroke (5.12%; 95%CI , 2.68% to 8.08%) within 7 days. The ABCD2 score washighly predictive of major recurrent stroke (AUC=0.76; 95%CI ,0.67 to 0.85, P <0.01), weaklypredictive of minor stroke (AUC=0.57; 95%CI , 0.42 to 0.70, P =0.18), and inversely related to riskof recurrent TIA (AUC=0.34; 95% CI , 0.22 to 0.59, P <0.01) (overall heterogeneity, P <0.001).Conclusion The ABCD2 score predicts severity of recurrent events after TIA, high scores beingassociated with major recurrent stroke and low scores with high rates of recurrent TIA.

Key words: Ischemic attack; transient; ABCD2 score; Forecasting; Risk factors