中国卒中杂志 ›› 2009, Vol. 4 ›› Issue (09): 715-720.

• 论著 • 上一篇    下一篇

CT灌注原始图像与CT血管原始图像的比较影像学研究

王效春,高培毅,林燕,薛静,刘光锐,马丽,王晨   

  1. 首都医科大学附属北京天坛医院神经影像中心
  • 收稿日期:2009-07-07 修回日期:2009-06-07 出版日期:2009-09-20 发布日期:2009-09-20
  • 通讯作者: 高培毅

Comparative Study of CT Perfusion Source Imaging and CT Angiography SourceImaging in Acute Stroke

WANG Xiao-Chun, GAO Pei-Yi, LIN Yan, et al   

  • Received:2009-07-07 Revised:2009-06-07 Online:2009-09-20 Published:2009-09-20
  • Contact: GAO Pe-Yi

摘要:

目的 比较计算机断层扫描灌注原始图像(computed tomography perfusion source imaging,CTP-SI)与计算机断层扫描血管原始图像(computed tomography angiography source imaging,CTA-SI)在超急性期缺血性卒中诊断中的价值。 方法 43例急性缺血性卒中(发病时间<9h)的患者行“一站式CT”扫描,根据动脉期与静脉期CTP-SI Alberta卒中早期CT评分(Alberta Stroke Program Early CT Score,ASPECTS)将患者分为两组:不匹配组和匹配组。分析基线CTA-SI、动脉期及静脉期CTP-SI ASPECTS,并与随访影像ASPECTS进行对照。 结果 匹配组,CTA-SI与动脉期和静脉期CTP-SI ASPECTS之间的差异无统计学意义(P=0.082,0.330);不匹配组,CTA-SI与动脉期和静脉期CTP-SI ASPECTS之间的差异存在统计学意义(P=0.007,0.001)。多元线性回归结果显示,匹配组CTA-SI和静脉期CTP-SI与随访影像ASPECTS的线性关系均存在统计学意义(P=0.007,0.040);不匹配组只有静脉期CTP-SI与随访影像ASPECTS之间的线性关系存在统计学意义(P=0.003)。 结论 与CTA-SI相比,CTP-SI也可以判断缺血的脑组织;并且,CTP-SI在鉴别梗死与非梗死的缺血脑组织方面存在优势。

关键词: 体层摄影术; X线计算机; 再灌注; 血管; 脑梗死

Abstract:

Objective To compare the diagnostic value of CTP-SI(computed tomography perfusion source imaging) and CTA-SI(computed tomography angiography source imaging) in acute stroke less than 9 hours. Methods "One-stop shop" CT examination were performed in 43 patients with symptoms of acute stroke less than 9 hours. ASPECTS(Alberta Stroke Program Early CT Score) were analyzed on arterial phase CTP-SI, venous phase CTP-SI and CTA-SI, then compared the baseline ASPECTS with the follow-up imaging 2 to 7 days. Results The ASPECTS measured on CTA-SI, arterial phase CTP-SI and venous phase CTP-SI had no significant difference(P=0.082; 0.330) in match group, however, in mismatch group, the difference had statistic significance(P=0.007; 0.001). The linear regression results suggest statistic significance between CTA-SI, venous phase CTP-SI and follow-up imaging studies(P=0.007; 0.040)in match group, While, the statistic significance was only found between venous phase CTP-SI and follow-up imaging studies(P=0.003). Conclusion Compared with CTA-SI, CTP-SI provides similar information in predicting ischemic tissue; Furthermore, CTP-SI provides more accurate information to CTA-SI about irreversible and reversible ischemic tissue.

Key words: Tomography; x-ray computed; Perfusion; Blood vessels; Brain infarction