1 Adeoye O, Broderick JP. Advances in the management

of intracerebral hemorrhage[J]. Nat Rev Neurol, 2010,

6:593-601.

2 van Asch CJ, Luitse MJ, Rinkel GJ, et al. Incidence,

case fatality, and functional outcome of intracerebral

haemorrhage over time, according to age, sex, and

ethnic origin:a systematic review and meta-analysis[J].

Lancet Neurol, 2010, 9:167-176.

3 Morgenstern LB, Hemphill JC 3rd, Anderson C, et

al. Guidelines for the management of spontaneous

intracerebral hemorrhage:a guideline for healthcare

professionals from the American Heart Association/

American Stroke Association[J]. Stroke, 2010, 41:2108-

2129.

4 Garg RK, Liebling SM, Maas MB, et al. Blood pressure

reduction, decreased diffusion on MRI, and outcomes

after intracerebral hemorrhage[J]. Stroke, 2012, 43:67-

71.

5 Herweh C, Jüttler E, Schellinger PD, et al. Evidence

against a perihemorrhagic penumbra provided by

perfusion computed tomography[J]. Stroke, 2007,

38:2941-2947.

6 Mayer SA, Lignelli A, Fink ME, et al. Perilesional

blood flow and edema formation in acute intracerebral

hemorrhage:a SPECT study[J]. Stroke, 1998, 29:1791-

1798.

7 Schellinger PD, Fiebach JB, Hoffmann K, et al.

Stroke MRI in intracerebral hemorrhage:is there a

perihemorrhagic penumbra?[J]. Stroke, 2003, 34:1674-

1679.

8 Za z ulia AR, Di r inger MN, Videen TO, et al.

Hypoperfusion without ischemia surrounding acute

intracerebral hemorrhage[J]. J Cereb Blood Flow

Metab, 2001, 21:804-810.

9 Kim-Han JS, Kopp SJ, Dugan LL, et al. Perihematomal

mitochondr ial dysfunction af ter int racerebral

hemorrhage[J]. Stroke, 2006, 37:2457-2462.

10 Prabhakaran S, Gupta R, Ouyang B, et al. Acute brain

infarcts after spontaneous intracerebral hemorrhage:a

diffusion-weighted imaging study[J]. Stroke, 2010,

41:89-94.

11 Kimberly WT, Gilson A, Rost NS, et al. Silent ischemic

infarcts are associated with hemorrhage burden in

cerebral amyloid angiopathy[J]. Neurology, 2009,

72:1230-1235.

12 Arsava EM, Kayim-Yildiz O, Oguz KK, et al. Elevated

admission blood pressure and acute ischemic lesions

in spontaneous intracerebral hemorrhage[J]. J Stroke

Cerebrovasc Dis, 2013, 22:250-254.

13 Gregoire SM, Charidimou A, Gadapa N, et al.

Acute ischaemic brain lesions in intracerebral

haemorrhage:multicentre cross-sectional magnetic

resonance imaging study[J]. Brain, 2011, 134:2376-

2386.

14 Menon RS, Burgess RE, Wing JJ, et al. Predictors

of highly prevalent brain ischemia in intracerebral

hemorrhage[J]. Ann Neurol, 2012, 71:199-205.

15 Kang DW, Han MK, Kim HJ, et al. New ischemic

l e s ion s c o ex i s t i ng wi t h a c ut e i nt r a c e r ebr a l

hemorrhage[J]. Neurology, 2012, 79:848-855.

16 Prabhakaran S, Naidech AM. Ischemic brain injury

after intracerebral hemorrhage:a critical review[J].

Stroke, 2012, 43:2258-2263.

17 Paulson OB, Waldemar G, Schmidt JF, et al. Cerebral

circulation under normal and pathologic conditions[J].

Am J Cardiol, 1989, 63:2C-5C.

18 Ma B, Zhang J. Nimodipine treatment to assess a

modified mouse model of intracerebral hemorrhage[J].Brain Res, 2006, 1078:182-188.

19 Zia E, Pessah-Rasmussen H, Khan FA, et al. Risk

factors for primary intracerebral hemor rhage:a

population-based nested case-control study[J].

Cerebrovasc Dis, 2006, 21:18-25.

20 Plesea IE, Camenita A, Georgescu CC, et al. Study

of cerebral vascular structures in hypertensive

intracerebral haemorrhage[J]. Rom J Morphol Embryol,

2005, 46:249-256.

21 Hill MD, Silver FL, Austin PC, et al. Rate of stroke

recurrence in patients with primary intracerebral

hemorrhage[J]. Stroke, 2000, 31:123-127.

22 Smith EE, Greenberg SM. Beta-amyloid, blood vessels,

and brain function[J]. Stroke, 2009, 40:2601-2606.

23 Maia LF, Mackenzie IR, Feldman HH. Clinical

phenotypes of cerebral amyloid angiopathy[J]. J Neurol

Sci, 2007, 257:23-30.

24 Smith EE, Vijayappa M, Lima F, et al. Impaired visual

evoked flow velocity response in cerebral amyloid

angiopathy[J]. Neurology, 2008, 71:1424-1430.

25 Xi G, Keep RF, Hoff JT. Mechanisms of brain injury

after intracerebral haemorrhage[J]. Lancet Neurol,

2006, 5:53-63.

26 Brouwers HB, Goldstein JN. Therapeutic strategies in

acute intracerebral hemorrhage[J]. Neurotherapeutics,

2012, 9:87-98.

27 Orakcioglu B. Perihemorrhagic ischemia occurs

in a volume-dependent manner as assessed by

multimodal cerebral monitoring in a porcine model of

intracerebral hemorrhage[EB/OL]. (2014-07-23) [2014-

10-27]. http://link.springer.com/article/10.1007%2

Fs12028-014-0027-3.

28 刘庆新, 张苏明. 急性脑出血继发缺血半暗带的研究

进展[J]. 国外医学:脑血管疾病分册, 2002, 10:191-194.

29 Rosell A, Vilalta A, Garcia-Berrocoso T, et al. Brain

perihematoma genomic profile following spontaneous

human intracerebral hemorrhage[J]. PLoS One, 2011,

6:e16750.

30 Lu A, Tang Y, Ran R, et al. Brain genomics of

intracerebral hemorrhage[J]. J Cereb Blood Flow

Metab, 2006, 26:230-252.

31 Burgess RE, Menon RS, Gibbons MC, et al. Presence

of DWI lesions is the strongest predictor of poor year

1 outcome in patients with primary intracerebral

hemorrhage[J]. Stroke, 2011, 42:E60-E60.