关键词: 脑分水岭梗死; 血压; 危险因素; 预后

Abstract: Objective To evaluate the relationship between patients’ blood pressure in the acute phase of cerebral watershed infarction and their outcomes. Methods In this study, a consecutive series of patients hospitalized for cerebral watershed infarction within 48 hours of onset were enrolled. Blood pressures were measured for each patient from admission to the third day. All clinical datas included basic information, stroke risk factors and supporting test results were collected. At 3 months after stroke onset, the late outcomes were measured by the modified Rankin score (mRs). Results A total of 106 patients were brought into the research. After grouped by the systolic blood pressure (SBP), a u-shaped relationship was observed between blood pressure and late outcome. The optimal level of SBP was 150-160 mmHg. After adjusted for other prognostic factors, multiple logistic regression analysis showed that, SBP declined every 10 mmHg below 150 mmHg, the risk of late poor outcome increased by 73.3% ( OR =1.733, 95% CI 1.073-2.799, P =0.024); when SBP≥160 mmHg, SBP had no significant relationship with poor outcome. Conclusion Low blood pressure in acute cerebral infarction watershed indicated a poor outcome, The optimal level of systolic blood pressure might be 150-160 mmHg.

Key words: Cerebral watershed infarction; Blood pressure; Risk factors; Prognosis