关键词: 脑梗死; 颈动脉; 内中膜; 血液动力学现象

Abstract: Objective To study the relationship between intima-medial thickness (IMT) and hemodynamicparameter of internal carotid artery in patients with acute anterior circulation cerebral infarction.Methods One hundred patients of cerebral infarction were measured by color Doppler ultrasound.The IMT of the bifurcating part of carotid artery (CCA) was measured. Then the internal carotidartery diameter, the peak systolic velocity (PSV) and minimum end-diastolic flow velocity (EDV) ofinternal carotid artery (ICA), the resisitive index (RI) and the pulsatility index (PI) were measuredby color Doppler ultrasound. They were compared to each other. We regarded normal of IMT asgroup one, thick of IMT as group two, and plaque as group three. To compare the diffenences of thehemodynamic parameters among the three groups.Results Double side IMT of internal carotid artery had a weak correlation with RI and PI (P <0.05)[Correlation coefficient between left IMT (IMTL) and RI: r =0.269, P =0.007; Correlation coefficientbetween right IMT(IMTR)and RI: r =0.211,P =0.035; Correlation coefficient between IMTL and PI:r =0.267, P =0.006; Correlation coefficient between IMTR and PI: r =0.205 (P =0.040)]. Double sideIMT of internal carotid artery had no significant difference with the internal carotid artery diameter,the PSV and EDV.Group plaque had a significant difference with group normal on RI and PI. LeftRI(RIL) was (1.17±0.28) vs (1.03±0.30); right RI(RIL)was (1.16±0.33) vs (1.05±0.17); left PI(PIL)was (0.64±0.08) vs (0.59±0.12); right PI(PIL)was (0.63±0.10) vs (0.61±0.06). P value was 0.036,0.041, 0.040 and 0.048 respectively.Conclusion There is relevance between IMT and hemodynamic parameter (RI and PI) of ICA inpatients with acute anterior circulation cerebral infarction. We observe change of IMT in order tokeep monitoring the hemodynamic developments of ICA, especially the plaque in the carotid artery.

Key words: Brain infarction; Carotid arteries; Intima-medial; Hemodynamic phenomena