›› 2011, Vol. 6 ›› Issue (07): 573-577.

• 综述 • 上一篇    下一篇

氧化应激在糖尿病增加缺血性卒中风险中的意义

赵敏   

  1. 北京市首都医科大学附属北京世纪坛医院内分泌科
  • 收稿日期:2010-10-21 修回日期:2010-09-21 出版日期:2011-07-20 发布日期:2011-07-20
  • 通讯作者: 赵敏

Importance of Oxidative Stress in Diabetes Increasing the Risk of Ischemic Stroke

ZHAO Min   

  • Received:2010-10-21 Revised:2010-09-21 Online:2011-07-20 Published:2011-07-20
  • Contact: ZHAO Min

摘要: 糖尿病患者发生卒中的风险较非糖尿病患者高,且发病时间早、程度严重。糖尿病患者往往处于更高的氧化应激水平。在糖尿病增加卒中风险、恶化卒中预后的机制中,氧化应激是一个关键介导环节。给予糖尿病患者抗氧化治疗,可有效减少血管事件的发生风险。

关键词: 糖尿病; 脑梗死; 氧化性应激

Abstract: The risk of stroke in patients with diabetes is higher than non-diabetic patients, and patients withdiabetes are easily suffered from stroke earlier and severer. Diabetes mellitus patients are oftenat a higher level of oxidative stress. Oxidative stress is a key mediating link in the mechanismof diabetes increasing the risk of stroke and worsening the prognosis of stroke. Antioxidants caneffectively reduce the risk of vascular events in patients with diabetes.

Key words: Diabetes mellitus; Brain infarction; Oxidative stress