Abstract: Objective To analyze the effect of transient ischemic attack(TIA) on cerebral ischemic tolerance.Methods Total 60 cases with cerebral infarction enrolled in our investigation, in which 30 cases had TIA within 72 hours as TIA group and 30 cases had no TIA history as control group.Results The TIA group had less cerebral infarction volume than control grou(8.2ml vs 10.6 ml, P<0.05), and had higher scores in European stroke scale(ESS) before treatment and after 15d, 30d, 90d treatment(62±22 vs 58±24, P<0.05; 70±28 vs 66±32, P<0.05; 80±20 vs 76±24, P<0.05; 82±18 vs 77±23, P<0.05).Conclusion TIA may improve cerebral ischemic tolerance and it has defnite clinical signifcance for decreasing the injury of brain cells in cerebral infarction.

Key words: Transient ischemic attack; Cerebral infarction; Cerebral ischemic tolerance

摘要： 目的 探讨短暂性脑缺血发作（TIA）在脑缺血耐受方面的临床意义。方法 选择30例TIA后72h内发生脑梗死的患者为试验组（TIA组），并随机选择30例无TIA史的脑梗死患者作对照组。结果 TIA组和脑梗死组在脑梗死体积、治疗前与治疗后15d，30d，90d的欧洲卒中量表（ESS）评分方面存在统计学差异（8.2 ml vs 10.6 ml；62±22 vs 58±24；70±28 vs 66±32；80±20 vs 76±24；82±18 vs 77±23； P均<0.05）。结论 TIA后发生脑梗死对减轻脑细胞损伤有一定临床意义。

关键词: 短暂性脑缺血发作; 脑梗死; 脑缺血耐受