关键词: 代谢综合征; 脑梗死; 发病率; 性别分布

Abstract: Objective To investigate the gender differences for the first-ever ischemic stroke (FIS) patientswith metabolic syndrome (MS) on basic levels.Methods Inpatients with FIS were enrolled consistently into our study from Aug. 2008 to Nov.2009. A cross-sectional study was conducted in these patients. According to the definition ofmetabolic syndrome by the International Diabetes Federation (IDF), the patients were divided intodifferent groups in order to comprehend the difference in gender.Results Six hundreds and two patients with FIS were enrolled in our study, the male was 411(68.3%), the female was 191 (31.7%). 234 inpatients were found with MS among in these patients,the male and female was all 117. The incidence of MS in the male and female was 28.5% and61.3% respectively. Compared to the female, the incidence of smoking and drinking were higherin the male (74.3% vs 14.5%, P <0.001 66.7% vs 4.3%, P <0.001). While compared to the male, theincidence of abdominal obesity and low high density lipoprotein (HDL), hypertension were higherin the female (79.1% vs 34.8%, P <0.001; 62.8% vs 38.9%, P <0.001; 97.4% vs 89.1%, P =0.024).The incidence of large artery atherosclerosis (LAA) stroke and non-LAA stroke was 67.4% vs48.4% (P =0.011) in the female with MS, when compared to the female without MS. While in themale, it was 29.2% vs 25.3% (P =0.490), when the two group were compared.Conclusion The incidence of MS in FIS patients was much higher in the female than that in themale. Smoking and drinking were common risk factors in the man with MS than those in thewoman, but abdominal obesity and low HDL, hypertension were common risk factors in the women.The female with MS had the trend to be LAA stroke more easily than the female without MS, butthis feature was not found in the male.

Key words: Metabolic syndrome; Brain infarction; Incidence; Sex distribution