Development and Reliability and Validity Testing of the Intravenous Thrombolysis Intention Scale for Acute Ischemic Stroke

doi:10.3969/j.issn.1673-5765.2025.04.016

Abstract

Abstract: Objective To develop an intravenous thrombolysis intention scale for acute ischemic stroke and evaluate its reliability and validity.
Methods This study used the theory of planned behavior as a guiding framework, forming an initial draft of the scale through literature analysis, Delphi expert consultation, and pre-survey. From July to August 2023, a questionnaire survey was conducted at three screening sites for high-risk stroke populations in Zhengzhou, Henan province, and the scale was analyzed for item analysis, reliability testing, and structural validity assessment. From September to October 2023, another survey was conducted to carry out confirmatory factor analysis and criterion-related validity assessment.
Results The intravenous thrombolysis intention scale for acute ischemic stroke comprised one overall evaluation item and three dimensions, totaling 13 items. The content validity index at the scale level was 0.9. Exploratory factor analysis extracted three common factors, contributing to a cumulative variance rate of 70.515% after rotation. The Cronbach’s α coefficient of the scale was 0.904, the split-half reliability was 0.840, and the test-retest reliability was 0.872. The results of the confirmatory factor analysis indicated that the scale demonstrated robust convergent and discriminant validity. The correlation coefficient between the overall scale score and the chronic disease health literacy scale score was 0.671 (P<0.001), and the correlation coefficient with respondents’ perceived risk of intracerebral hemorrhage complications after thrombolysis was -0.402 (P<0.001).
Conclusions The intravenous thrombolysis intention scale for acute ischemic stroke exhibits good reliability and validity, and can be used to assess the intention level of intravenous thrombolysis in cases of acute ischemic stroke.

Key words: Acute ischemic stroke; Intravenous thrombolysis; Intention; Scale development; Reliability; Validity

摘要： 目的编制急性缺血性卒中静脉溶栓意向量表并对其信效度进行检验。
方法本研究以计划行为理论为指导框架，通过文献分析、德尔菲专家函询和预调查形成量表初稿。于2023年7—8月选取河南省郑州市3个卒中高危人群筛查点进行问卷调查，并对量表进行项目分析、信度检验及结构效度分析，2023年9—10月进行再次调查，对量表进行验证性因子分析和效标关联效度分析。
结果急性缺血性卒中静脉溶栓意向量表共包括1个总评价条目和3个维度，共13个条目。量表水平的内容效度指数为0.9；探索性因子分析共提取3个公因子，旋转后累积方差贡献率为70.515%；量表的Cronbach’s α系数为0.904，折半信度为0.840，重测信度为0.872；验证性因子分析结果显示，量表的聚合效度和区分效度良好；量表总分与慢性病患者健康素养量表得分的相关系数为0.671（P<0.001），与被调查者溶栓后脑出血并发症风险主观感知程度的相关系数为-0.402（P<0.001）。
结论急性缺血性卒中静脉溶栓意向量表具有良好的信效度，可用于测量急性缺血性卒中静脉溶栓意向水平。

关键词: 急性缺血性卒中; 静脉溶栓; 意向; 量表开发; 信度; 效度

CLC Number:

GUO Yuanli, GAO Renke, YANG Caixia, FAN Wenfeng, GUO Li’na, DONG Xiaofang, LYU Peihua, GAO Huanhuan, MA Keke. Development and Reliability and Validity Testing of the Intravenous Thrombolysis Intention Scale for Acute Ischemic Stroke[J]. Chinese Journal of Stroke, 2025, 20(4): 511-518.

郭园丽, 高任轲, 杨彩侠, 范文凤, 郭丽娜, 董小方, 吕培华, 高欢欢, 马珂珂. 急性缺血性卒中静脉溶栓意向量表的编制及信效度检验[J]. 中国卒中杂志, 2025, 20(4): 511-518.

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