Chinese Journal of Stroke ›› 2013, Vol. 8 ›› Issue (02): 142-146.

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Research Advance on Imaging Findings of Post-stroke Depression

  

  1. *Department of Radiology, Beijing Tiantan Hospital, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China
  • Received:2012-10-19 Online:2013-02-20 Published:2013-02-20

卒中后抑郁的影像学研究进展

苏录1,3,薛静1,2,3,张宁4,王春雪4   

  1. 1100050 北京
    首都医科大学附属北京天坛医院放射科
    2北京市神经外科研究所
    3磁共振成像脑信息学北京市重点实验室(NO:BZ0133)
    4首都医科大学附属北京天坛医院神经内科
  • 通讯作者: 薛静 xuejing2006@126.com
  • 基金资助:

    首都医学发展科研基金资助项目(2009-3105)
    北京市自然科学基金
    (7102050)

Abstract:

Post-stroke depression(PSD) is a common complication of cerebrovascular disease, which may impede neurological rehabilitation of patients with PSD, even kill more patients suffering from stroke. Reports on the incidence of PSD vary from each other greatly; it is concentrated between 20% and 50%. Although regular imaging plays a significant role on the foundation and supports the hypothesis of limbic-cortical-striatal-pallidal-thalamic(LCSPT) circuit, it still cannot serves good to early identify of PSD compared with functional magnetic resonance imaging(MRI). Hence, functional MRI would lay the foundation and promote early identification and prevention of PSD on the basis of nowadays survey on depression.

Key words: Depression; Stroke; Magnetic resonance imaging

摘要:

卒中后抑郁(post-stroke depression,PSD)是卒中后的常见并发症,不仅影响卒中患者的精神和神经功能恢复,甚至会增加患者的致残率和死亡率。常规影像学在PSD的相关解剖学部位与边缘系统-前额叶皮层-纹状体-苍白球-丘脑神经解剖环路假说的确立和巩固方面具有重要作用,但并不能对PSD进行早期的预测,功能磁共振在PSD的早期识别上具有优势,为PSD的研究提供了支持。

关键词: 抑郁; 卒中; 磁共振成像