关键词: 缺血性卒中; 卵圆孔未闭; 房间隔缺损; 经导管; 封堵

Abstract:

Objective To summarize the perioperative clinical characteristics and management experience of transcatheter closure of atrial septal abnormalities (patent foramen ovale[PFO], atrial septal defect[ASD]) in patients with ischemic stroke. Methods Ischemic stroke patients who underwent transcatheter closure of atrial septal abnormalities at Beijing Tiantan Hospital between May 2015 and May 2016 were enrolled. The blood pressure and heart rate of patients with ischemic stroke complicated with ASD before, during and after transcatheter closure of PFO/ASD were analyzed. Results Interventional occlusion was successfully performed in 27 patients. The patients were discharged in average 2 days after the operation. All patients had no symptoms and the occluder were in good position. No occluder malposition and thrombus, no neurological recurrences were observed. There were no statistically significant differences in blood pressure before, during and after treatment; there were statistically significant differences in heart rate before, during and after treatment (70.72±9.18 beats/min, 77.48±8.69 beats/min, 67.69±8.73 beats/min, P <0.01). Conclusion Perioperative management of transcatheter PFO or ASD closure can help to reduce postoperative complications and improve the success rate of operation.

Key words: Ischemic stroke; Patent foramen ovale; Atrial septal defect; Transcatheter, Closure