中国卒中杂志 ›› 2017, Vol. 12 ›› Issue (02): 152-154.DOI: 10.3969/j.issn.1673-5765.2017.02.010

• 专题综述 • 上一篇    下一篇

显微光学切片断层成像技术在卒中研究中的应用

潘超,张萍,唐洲平   

  1. 430030 武汉华中科技大学同济医学院附属同济医院神经内科
  • 收稿日期:2016-12-23 出版日期:2017-02-20 发布日期:2017-02-20
  • 通讯作者: 唐洲平 ddjtzp@163.com
  • 基金资助:

    国家自然科学基金面上项目(81171089,81471201)

Application of Micro-optical Sectioning Tomography (MOST) in Stroke Study

  • Received:2016-12-23 Online:2017-02-20 Published:2017-02-20

摘要:

卒中是一类高发病率、致死率、致残率的中枢神经系统疾病。目前对卒中的发病机制、发 病后的病理生理变化、卒中后神经血管保护的研究尚不深入。显微光学切片断层成像技术能用于绘 制不同脑疾病鼠全脑的数字化图谱。通过显微光学切片断层成像技术获取的脑连接图谱为卒中研究 提供了重要的基础性实验数据。本文就显微光学切片断层成像技术的发展现状进行介绍,并探讨其 在卒中领域的研究价值。

文章导读: 显微光学切片断层成像技术在卒中研究领域前景广阔。

关键词: 显微光学切片断层成像; 卒中; 脑图谱

Abstract:

Stroke is a prevalent central nervous system disease characterized by its high mortality and morbidity rates. The researches about the pathogenesis of stroke, changes in pathophysiology and neurovascular protection were superficial. Micro optical sectioning tomography (MOST) is developed to map digital whole brain atlas of different diseases. The neural connection mapping provides an important data foundation for stroke research. This review will introduce the present situation of MOST and discuss the value of MOST in stroke study.

Key words: Micro-optical sectioning tomography (MOST); Stroke; Brain atlases