血管性帕金森综合征的临床特征及神经影像学研究进展

doi:10.3969/j.issn.1673-5765.2021.09.015

摘要/Abstract

摘要： 血管性帕金森综合征（vascular parkinsonism，VaP）是由脑血管疾病引起的继发性帕金森综合征，与帕金森病（Parkinson's disease，PD）有类似的临床特点，临床表现以下半身运动障碍为主，常伴有锥体束征、假性延髓麻痹、痴呆、失禁等。为进一步认识VaP，本文就其临床特征、神经影像学进展进行综述。VaP的发病机制尚未完全明确，临床上缺乏确切的诊断标准，有必要进行更深入的研究，以更好地诊治VaP。

文章导读： VaP临床表现具有很大的异质性，主要症状为下半身帕金森综合征，表现为左右对称的步态异常，但静止

关键词: 血管性帕金森综合征; 临床特征; 运动症状; 非运动症状; 神经影像; 间碘苯甲呱; 碘氟潘单光子发射计算机断层扫描

Abstract: Vascular parkinsonism (VaP) is a secondary parkinsonism caused by cerebral vascular disorders. It has many similar clinical characteristics with Parkinson's disease (PD). The main clinical features of VaP are lower limb dyskinesia, accompanied by pyramidal tract syndrome, pseudobulbar paralysis, dementia, urinary incontinence, etc. This article reviewed the progress of clinical and neuroimaging features of VaP, to deepen the understanding of VaP. The pathogenesis of VaP is still unclear, and further research is needed to better dignose and treat VaP.

Key words: Vascular parkinsonism; Clinical feature; Motor symptom; Non-motor symptom;
Neuroimaging; 123I-metaiodobenzylguanidine; 123I-ioflupane single photon emission computed
tomography

罗倩, 彭思佳, 王笑瑗, 唐宇凤, 吴云成. 血管性帕金森综合征的临床特征及神经影像学研究进展[J]. 中国卒中杂志, 2021, 16(09): 967-970.

LUO Qian, PENG Si-Jia, WANG Xiao-Yuan, TANG Yu-Feng, WU Yun-Cheng. Progress of Clinical and Neuroimaging Features of Vascular Parkinsonism[J]. Chinese Journal of Stroke, 2021, 16(09): 967-970.

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