关键词: 动脉溶栓; 脑梗死; 尿激酶

Abstract: Objective To evaluate the safety and clinical efficacy of intra-arterial thrombolysis using urokinasein patients with acute ischemic stroke.Methods Total 7 patients of acute ischemic stroke in 6h were treated with intra-arterialthrombolysis using urokinase. They were assessed by neurologists using National Institutes ofHealth Stroke Scale(NIHSS) score at admittance to the hospital, after the treatment and 14d afterthe treatment.Results Seven patients achieved complete recanalization. It was improved obviously of theneurologic function defect of the 7 patients after 14d. None of cerebral hemorrhage was observed.Conclusion Intra-artery thrombolysis therapy using urokinase for acute ischemic stroke might besafe and effective, but we need a large sample, randomized and control study to confirm.

Key words: Intra-arterial thrombolysis; Cerebral infarction; Urokinase