›› 2008, Vol. 3 ›› Issue (01): 15-19.

• 论著 • 上一篇    下一篇

156 例后循环梗死患者的预后分析

施国文,李焰生,林岩,徐群,熊昕丽,邹静   

  1. 上海市上海交通大学医学院附属仁济医院神经内科
  • 收稿日期:2007-09-25 修回日期:2007-08-25 出版日期:2008-01-20 发布日期:2008-01-20
  • 通讯作者: 李焰生

Prognostic Analysis of 156 Patients with Posterior Circulation Infarction

SHI Guo-Wen,LI Yan-Sheng, LIN Yan, et al.   

  • Received:2007-09-25 Revised:2007-08-25 Online:2008-01-20 Published:2008-01-20
  • Contact: LI Yan-Sheng

摘要: 目的 评估后循环梗死患者的预后并分析其相关因素。方法 回顾性分析2004~2006年在我院神经内科住院且发病时间<7 d的急性后循环梗死并且随访资料完整的病例156例。所有患者在入院时均进行头颅MRI检查,证实在后循环供血区存在缺血病灶。在病后2年内(平均随访时间13.4±5.0月)对患者进行残障量表(mRS)、Barthel指数(BI)评估,了解患者的预后情况。评价危险因素、病变部位和预后的关系。结果 156例后循环梗死患者中,病后2年内无残障及轻度残障(mRS 0~3分)者占76.3%,严重残障(mRS 4~5分)者占19.9%,死亡者占3.8%。mRS和BI两种评估方法一致性较好(P<0.01)。BI评估的多因素回归分析显示年龄(OR 1.079,95%CI 1.034~1.125,P <0.01)、多病灶(OR 3.463,95%CI 1.294~9.267,P=0.013)、卒中史(OR 2.505,95%CI 1.103~5.685,P=0.025)与病后2年的预后相关。结论 后循环梗死患者的总体预后良好,死亡率低。年龄小、单病灶、既往无卒中史者预后较好。

关键词: 后循环缺血性卒中; 危险因素; 预后

Abstract: Objective To evaluate the determinants of the prognosis of patients with posterior circulationischemic stroke.Methods Total 156 patients with posterior circulation ischemic stroke within 7 days admittedduring 2004-2006 were analyzed retrospectively. All patients were undertaken magnetic resonanceimaging(MRI) on admission and ischemic lesions were identified at the posterior circulationterritories. The patients were evaluated within 2 years by modified Rankin scale(mRS) and Bathelindex(BI) to investigate the relationships between risk factors, lesion locations and prognosis.Results Of the 156 patients, 76.3% showed no or mild disability(mRS 0-3) and 19.9% showedsevere disability(mRS 4-5) within 2 years. Mortality was 3.8% of all the patients. There wassignificant coincidence between mRS and BI(P <0.01). When evaluated by BI, prognosis within 2years of the patients were associated with age(OR 1.079, 95%CI 1.034-1.125, P <0.01), multiplelesions(OR 3.463, 95%CI 1.294-9.267, P =0.013), stroke history(OR 2.505, 95%CI 1.103-5.685,P =0.025) by the logistic procedure.Conclusion Majority of the patients with posterior circulation ischemic stroke have goodprognosis. Patients who are young, with single lesion and no stroke history have better prognosis.

Key words: Posterior circulation ischemic stroke; Risk factor; Prognosis