›› 2009, Vol. 4 ›› Issue (02): 159-162.

• 综述 • 上一篇    下一篇

内皮祖细胞与卒中

陈立云1,Alex F. Chen2,王拥军1   

  1. 1首都医科大学附属北京天坛医院神经内科2Department of Vascular Surgery, University of Pittsburgh Medical Center. Pittsburgh, PA 15213, USA
  • 收稿日期:2008-12-08 修回日期:1900-01-01 出版日期:2009-02-20 发布日期:2009-02-20

Endothelial Progenitor Cells and Stroke

CHEN Li-Yun, Alex F. Chen, WANG Yong-Jun.   

  1. Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
  • Received:2008-12-08 Revised:1900-01-01 Online:2009-02-20 Published:2009-02-20

摘要: 内皮祖细胞(endothelial progenitor cells,EPC)作为成年干细胞的一种,近些年对其研究较热,但多数集中在心血管病方面,在卒中方面的研究有限。对动物和人类的研究表明EPC可作为血管病的预测因子,并且EPC以及对EPC的调节有可能用于脑血管病的治疗。本文对EPC在卒中方面的研究进展做一综述。

关键词: 卒中; 内皮细胞; 干细胞; 神经再生; 血管发生

Abstract:

As a population of adult stem cells, endothelial progenitor cells (EPC) have been focused on by many researchers in these years. However, most of studies on EPCs are on cardiovascular disease instead of stroke. It was found that EPC could be a biomarker of cardiovascular risk and EPC transplantation or regulation of EPC mobilization may play a role in the therapy of stroke. In this review, we will summarize the developments of researches on EPC and stroke.

Key words: Stroke; Endothelial cells; Stem cells; Nerve regeneration; Angiogenesis