关键词: 脑出血; 格拉斯哥昏迷量表

Abstract: Objective To identify the predictors correlated with the prognosis 90 days after hypertensive cerebral hemorrhage.Methods 73 spontaneous hypertensive cerebral hemorrhage patients within 3 hours after onset were enrolled into our study during January 2006 to October 2007. The demographic data, past history and laboratory examination were recorded. We assessed the neurologic deficit at several time spot using the U.S National Institutes of Health Stroke Scale(NIHSS), Glasgow Coma Scale(GCSe and modified Rankin Scale(mRS). Computed tomography scans at baseline, 24±3hours, and 72±3hours were performed separately. All factors correlated with 90 days’ prognosis and hematoma volume in baseline were analyzed.Results Among all recruit patients, Independent-Samples T Test revealed those factors including lactate dehydrogenase(P=0.026), erythrosedimentation(P=0.001), blood sedimentation(P=0.001), creatinine(P=0.036), glasgow coma scale(GCS) at baseline(P=0.001), fibrinogen(P=0.012), medlineshift, infection, NIHSS(P=0.002), GCS(P=0.001), infection while hospitalization (P=0.001), operation(P=0.014), hematoma size(P<0.01), absolute edema size(P<0.01), hematoma enlargement in 24 hours(P=0.002), bleeding ruptured into ventricular system(P=0.001), medline shift(P=0.003) were correlated with 90 days outcome.Conclusion In this study, we found factors including hematoma volume, absolute perihemotoma edema, blood ruptured into ventricular system, hyperfibrinogenemia, creatinine, lactate dehydrogenase, erythrosedimentation medlineshift, infection, NIHSS, GCS correlated to the poor outcome. In clinical treatment, we should focus on the primary lesions so to improving the outcome.

Key words: Cerebral hemorrhage; Glasgow coma scale; Prognosis