›› 2010, Vol. 5 ›› Issue (10): 864-871.

• 综述 • 上一篇    下一篇

围产期卒中

江潍1,江滨2   

  1. 1 江西省乐平市乐平市人民医院妇产科2首都医科大学北京市神经外科研究所神经流行病学室
  • 收稿日期:2010-05-10 修回日期:2010-04-10 出版日期:2010-10-20 发布日期:2010-10-20
  • 通讯作者: 江滨

Perinatal Stroke

JIANG Wei*, JIANG Bin.   

  • Received:2010-05-10 Revised:2010-04-10 Online:2010-10-20 Published:2010-10-20
  • Contact: JIANG Bin

摘要: 常见的围产期卒中的三个主要亚型为动脉性缺血性卒中(arterial ischemic stroke,AIS)、大脑静脉窦血栓形成(cerebral venous sinus thrombosis,CVST)和出血性卒中(hemorrhagic Stroke,HS)。围产期是人生卒中相对高发的特殊时期,据估计围产期AIS的发病率在17~43.4/10万活产;新生儿期CVST的发病率在41/10万活产;足月婴儿HS的发病率为6.7/10万活产。癫发作是新生儿卒中急性期最常见的表现;在急性期过后,可能会遗留认知障碍和感觉损害、脑瘫(运动功能障碍)和癫等后遗症。由于无明显或无特定的临床表现,围产期卒中的临床诊断主要依赖超声和神经影像学的诊断。对围产期卒中的流行规律、发病机制、诊断、治疗、预防和康复的认识,急待进一步研究。

关键词: 卒中; 围产期; 婴儿; 新生; 婴儿死亡率

Abstract: Perinatal stroke has 3 common types of arterial ischemic stroke (AIS), cerebralvenous sinus thrombosis (CVST) and hemorrhagic stroke (HS). Perinatal period is a specialtime in a life with higher risk of stroke, with estimated incidence of 17-43.4/100 000 live birthsin AIS, 41/100 000 in CVST and 6.7/100 000 in HS. Seizure is the most common clinicalpresentation in acute stage of perinatal stroke; cognitive and sensory impairments, cerebral plasy,and epilepsy may present in some cases in following stage. Because of no typical or specifiedclinical presentation, diagnostic evaluation for the perinatal stroke is mainly dependent on cranialultrasound and neuro-imaging of computed tomography/magnetic resonance imaging. Lack ofknowledge on perinatal stroke in epidemiology, pathogenic mechanism, diagnosis, treatment,prevention and rehabilitation calls for further study.

Key words: Stroke; perinatal; Infant; newborn; Infant mortality