关键词: 脑梗死; 神经外科手术; 减压术; 外科

Abstract: Objective To compare the clinical outcome of decompressive hemicraniectomy surgery incombination with medical treatment and medical treatment alone in large cerebral infarction.Methods This study is a prospective clinical research, and 71 patients with a large cerebralinfarction were involved. Twenty-three patients received decompressive hemicraniectomy surgeryin combination with medical treatment (surgery group), 48 patients only received medical treatment(conservative group). The outcome measure was the modified rankin scale (mRS) at 6 months afterthe onset of infarction.Results There were 39.1% of the patients in the surgery group got good outcomes in 6 monthsfollow-up, and 16.7% in conservative group (P =0.042).Conclusion Decompressive hemicraniectomy surgery in combination with medical treatment canimprove the clinical outcome of the large cerebral infarction patients.

Key words: Brain infarction; Neurosurgical procedures; Decompression; surgical